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Thrombocytopenia after COVID-19 vaccination.新冠疫苗接种后的血小板减少症。
J Autoimmun. 2021 Sep;123:102712. doi: 10.1016/j.jaut.2021.102712. Epub 2021 Jul 27.
2
Myocarditis after vaccination against covid-19.接种新冠疫苗后发生的心肌炎
BMJ. 2021 Dec 16;375:n3090. doi: 10.1136/bmj.n3090.
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COVID-19 Vaccines and Thrombosis-Roadblock or Dead-End Street?COVID-19 疫苗与血栓：路障还是死胡同？
Biomolecules. 2021 Jul 13;11(7):1020. doi: 10.3390/biom11071020.
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Acute Myocarditis Following COVID-19 mRNA Vaccination in Adults Aged 18 Years or Older.成年人接种 COVID-19 mRNA 疫苗后出现急性心肌炎。
JAMA Intern Med. 2021 Dec 1;181(12):1668-1670. doi: 10.1001/jamainternmed.2021.5511.
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Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data.辉瑞/BioNTech 和阿斯利康 ChAdOx1 nCoV-19 疫苗接种后血栓和出血事件：欧洲数据分析。
J Autoimmun. 2021 Aug;122:102685. doi: 10.1016/j.jaut.2021.102685. Epub 2021 Jun 23.
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Severe immune thrombocytopenia after COVID-19 vaccination: Report of four cases and review of the literature.新型冠状病毒肺炎疫苗接种后严重免疫性血小板减少症：4例报告及文献复习
Blood Cells Mol Dis. 2021 Dec;92:102615. doi: 10.1016/j.bcmd.2021.102615. Epub 2021 Oct 7.
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Coagulopathies after Vaccination against SARS-CoV-2 May Be Derived from a Combined Effect of SARS-CoV-2 Spike Protein and Adenovirus Vector-Triggered Signaling Pathways.接种 SARS-CoV-2 疫苗后发生的凝血功能障碍可能源于 SARS-CoV-2 刺突蛋白和腺病毒载体触发的信号通路的综合作用。
Int J Mol Sci. 2021 Oct 6;22(19):10791. doi: 10.3390/ijms221910791.
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Age-Stratified Risk of Cerebral Venous Sinus Thrombosis After SARS-CoV-2 Vaccination.新型冠状病毒疫苗接种后大脑静脉窦血栓形成的年龄分层风险。
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Immune thrombocytopenic purpura after vaccination with COVID-19 vaccine (ChAdOx1 nCov-19).接种新型冠状病毒疫苗（ChAdOx1 nCoV-19）后发生免疫性血小板减少性紫癜
Blood. 2021 Sep 16;138(11):996-999. doi: 10.1182/blood.2021012790.

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Off-the-Shelf Large Language Models for Causality Assessment of Individual Case Safety Reports: A Proof-of-Concept with COVID-19 Vaccines.用于个体病例安全报告因果关系评估的现成大语言模型：以新冠疫苗为例的概念验证
Drug Saf. 2025 Mar 12. doi: 10.1007/s40264-025-01531-y.
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COVID-19 vaccination and the risk of autoimmune diseases: a Mendelian randomization study.COVID-19 疫苗接种与自身免疫性疾病风险：一项孟德尔随机化研究。
Front Public Health. 2024 Mar 14;12:1322140. doi: 10.3389/fpubh.2024.1322140. eCollection 2024.
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Pernicious Anemia Following COVID-19 Vaccination: A Report of Two Cases.新冠疫苗接种后发生的恶性贫血：两例报告
Int J Hematol Oncol Stem Cell Res. 2023 Jul 1;17(3):220-223. doi: 10.18502/ijhoscr.v17i3.13312.
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COVID-19 vaccination in patients with primary immunodeficiencies: an international survey on patient vaccine hesitancy and self-reported adverse events.原发性免疫缺陷病患者的 COVID-19 疫苗接种：一项针对患者疫苗犹豫和自我报告不良事件的国际调查。
Front Immunol. 2023 Apr 18;14:1166198. doi: 10.3389/fimmu.2023.1166198. eCollection 2023.
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Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccines: A systematic review.新冠病毒疫苗接种后多发性硬化症 (MS) 和视神经脊髓炎谱系障碍 (NMOSD)：系统评价。
Rev Neurol (Paris). 2023 Apr;179(4):265-281. doi: 10.1016/j.neurol.2022.11.004. Epub 2023 Jan 17.
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Clinical characteristics in immune thrombocytopenia patients after COVID-19 vaccination.新型冠状病毒疫苗接种后免疫性血小板减少症患者的临床特征。
Hum Vaccin Immunother. 2022 Nov 30;18(6):2119043. doi: 10.1080/21645515.2022.2119043. Epub 2022 Sep 7.
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Adamalysins in COVID-19 - Potential mechanisms behind exacerbating the disease.COVID-19 中的 Adamalysins - 加重疾病的潜在机制。
Biomed Pharmacother. 2022 Jun;150:112970. doi: 10.1016/j.biopha.2022.112970. Epub 2022 Apr 15.
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Severe Immune Thrombocytopenia after COVID-19 Vaccination: Two Case Reports and a Literature Review.新冠病毒疫苗接种后发生严重免疫性血小板减少症：两例病例报告及文献复习。
Intern Med. 2022 May 15;61(10):1581-1585. doi: 10.2169/internalmedicine.9177-21. Epub 2022 Mar 19.
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Upper Limb Ischemia Due to Arterial Thrombosis after COVID-19 Vaccination.新冠疫苗接种后动脉血栓形成所致上肢缺血
Case Rep Med. 2022 Mar 9;2022:4819131. doi: 10.1155/2022/4819131. eCollection 2022.
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Cell fusion as a link between the SARS-CoV-2 spike protein, COVID-19 complications, and vaccine side effects.细胞融合作为严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突蛋白、新型冠状病毒肺炎（COVID-19）并发症和疫苗副作用之间的联系。
Oncotarget. 2021 Dec 7;12(25):2476-2488. doi: 10.18632/oncotarget.28088.

本文引用的文献

1
Thromboembolic events in younger women exposed to Pfizer-BioNTech or Moderna COVID-19 vaccines.辉瑞/生物科技或莫德纳 COVID-19 疫苗接种的年轻女性中的血栓栓塞事件。
Expert Opin Drug Saf. 2021 Nov;20(11):1451-1453. doi: 10.1080/14740338.2021.1955101. Epub 2021 Jul 26.
2
Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data.辉瑞/BioNTech 和阿斯利康 ChAdOx1 nCoV-19 疫苗接种后血栓和出血事件：欧洲数据分析。
J Autoimmun. 2021 Aug;122:102685. doi: 10.1016/j.jaut.2021.102685. Epub 2021 Jun 23.
3
Thrombocytopenia including immune thrombocytopenia after receipt of mRNA COVID-19 vaccines reported to the Vaccine Adverse Event Reporting System (VAERS).接种 mRNA COVID-19 疫苗后出现的血小板减少症，包括免疫性血小板减少症，已向疫苗不良事件报告系统（VAERS）报告。
Vaccine. 2021 Jun 8;39(25):3329-3332. doi: 10.1016/j.vaccine.2021.04.054. Epub 2021 Apr 30.
4
Thrombocytopenia with acute ischemic stroke and bleeding in a patient newly vaccinated with an adenoviral vector-based COVID-19 vaccine.患者在接种新型冠状病毒病腺病毒载体疫苗后新发血小板减少伴急性缺血性脑卒中及出血。
J Thromb Haemost. 2021 Jul;19(7):1771-1775. doi: 10.1111/jth.15347. Epub 2021 May 5.
5
Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination.接种 ChAdOx1 nCoV-19 疫苗后对血小板因子 4 的病理性抗体。
N Engl J Med. 2021 Jun 10;384(23):2202-2211. doi: 10.1056/NEJMoa2105385. Epub 2021 Apr 16.
6
SARS-CoV-2 Vaccine-Induced Immune Thrombotic Thrombocytopenia.严重急性呼吸综合征冠状病毒2型疫苗诱导的免疫性血栓性血小板减少症
N Engl J Med. 2021 Jun 10;384(23):2254-2256. doi: 10.1056/NEJMe2106315. Epub 2021 Apr 16.
7
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.接种 ChAdOx1 nCov-19 疫苗后发生血栓性血小板减少症。
N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840. Epub 2021 Apr 9.
8
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination.ChAdOx1新冠疫苗接种后的血栓形成和血小板减少症
N Engl J Med. 2021 Jun 3;384(22):2124-2130. doi: 10.1056/NEJMoa2104882. Epub 2021 Apr 9.
9
Thrombocytopenia following Pfizer and Moderna SARS-CoV-2 vaccination.辉瑞和莫德纳新冠疫苗接种后出现的血小板减少症。
Am J Hematol. 2021 May 1;96(5):534-537. doi: 10.1002/ajh.26132. Epub 2021 Mar 9.

Thrombocytopenia after COVID-19 vaccination.

作者信息

Kragholm Kristian, Sessa Maurizio, Mulvad Thomas, Andersen Mikkel Porsborg, Collatz-Christensen Helle, Blomberg Stig Nikolaj, Lippert Freddy, Mikkelsen Soren, Leutscher Peter, Melgaard Dorte, Torp-Pedersen Christian, Kristensen Soren Risom, Larsen Torben Bjerregaard, Sogaard Peter

机构信息

Department of Cardiology, Aalborg University Hospital, Denmark; Unit of Clinical Biostatistics and Epidemiology, Aalborg University Hospital, Denmark.

Faculty of Health Sciences, Department of Drug Design and Pharmacology, Metabolism and Inflammation Research Cluster, Pharmacovigilance Research Center, Copenhagen University, Denmark.

出版信息

J Autoimmun. 2021 Sep;123:102712. doi: 10.1016/j.jaut.2021.102712. Epub 2021 Jul 27.

DOI:10.1016/j.jaut.2021.102712
PMID:34332437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8313538/
Abstract
摘要