Kovalev L I, Puliaeva E V, Shishkin S S
Tsitol Genet. 1987 Sep-Oct;21(5):383-5.
The study of the polypeptide structure of cardiac muscle proteins of the inbred mice 129 Re + dy/dy by two-dimensional electrophoresis has revealed quantitative and qualitative variations in four polypeptides out of 161 analyzed ones. It is supposed that the protein fractions N 14 and O 13 may contribute to the development of cardiac pathology. Gene-dosage dependence is identified for the fraction O 13.
通过二维电泳对近交系小鼠129 Re + dy/dy心肌蛋白的多肽结构进行研究后发现,在分析的161种多肽中,有4种存在定量和定性变化。据推测,蛋白质组分N 14和O 13可能与心脏病理学的发展有关。已确定组分O 13存在基因剂量依赖性。