[The use of two-dimensional electrophoresis for the analysis of changes in the protein spectrum of the cardiac muscle during mouse ontogenesis].

Using two-dimensional polyacrylamide gel electrophoresis, an analysis of protein spectrum of cardiac muscle of C57BL/6Y mice in the course of ontogenesis was carried out. It was found that some genes expressed in the embryonic muscle are repressed in the course of differentiation. Seven major polypeptides were revealed during cardiac muscle growth. The methodological aspects of the use of two-dimensional electrophoresis are discussed.