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单孔腹腔镜与胸腔镜McKeown食管癌切除术的临床应用与分析

[Clinical application and analysis of single-port laparoscopic and thoracoscopic McKeown esophagectomy for esophageal cancer].

作者信息

Liu B, Qiu M L, Feng Z, Lin N L, Yu M J, Li X

机构信息

Department of Thoracic Surgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2021 Aug 3;101(29):2316-2321. doi: 10.3760/cma.j.cn112137-20201215-03359.

DOI:10.3760/cma.j.cn112137-20201215-03359
PMID:34333948
Abstract

To explore the application value of single-port laparoscopic and thoracoscopic McKeown esophagectomy for esophageal cancer. A retrospective study was conducted to collect clinical data of 34 patients with esophageal cancer who were admitted to the Department of Thoracic Surgery, the First Affiliated Hospital of Fujian Medical University, from August to November 2020. All of them, 24 males and 10 females aged from 43 to 75 with an average of (62±4) years, underwent single-port laparoscopic and thoracoscopic McKeown esophagectomy.In the thoracic part, esophageal separation and mediastinal lymph node dissection were performed with conventional 4-ports thoracoscopy in the left lateral-prone position. In the abdominal part, gastric separation and lymph node dissection were accomplished with single-port laparoscopic retrograde three-step gastric separation: firstly, the lesser omentum was dissociated, the left liver lobe was suspended with purse-string needle and thread, after that the left gastric blood vessel and lymph node was dissected; secondly, the esophageal hiatus was separated, and the gastric cardia was cut off; finally, the spleen and stomach ligaments were dissociated to complete these steps. The operation time,volume of intraoperative blood loss, time for out-of-bed activities, time of postoperative drainage tube removal,volume of thoracic drainage fluid, short-term postoperative commplications,the postoperative pathological diagnoses, the time of their discharge from hospital and results of follow-up were observed. All patients underwent successfully single-port laparoscopic and thoracoscopic esophagectomy without any conversion to open surgery; the operative time of the patients was 194-285 (240±21)min, including 53-105(60±13)min for the thoracic part and 40-73(49±7)min for the abdominal part. The volume of intraoperative blood loss was 15-110(60±20) ml. The numbers of mediastinal lymph node dissected and abdominal lymph nodes harvested were 10-25(13±3), 6-16(9±3)respectively. The 34 patients resumed out-of-bed activities on the 2nd to 3rd day after the operation. The thoracic closed drainage tube and left cervical drainage were removed 2 days after the operation. The thoracic Abel drainage tube was removed 5 days after the operation. The total volume of postoperative thoracic drainage fluid was 100-500(300±100)ml. No obvious sign of anastomotic leakage, anastomotic stenosis, chylothorax or gastric emptying disorder was found after the operation. Eight cases were complicated with temporal hoarseness, and 4 patients with pneumonia which was cured by antibiotics. The mean postoperative hospital stay was 8 days(6, 8), and patients were discharged after they could take a routine semi-liquid diet. The postoperative pathological diagnoses of all patients were squamous cell carcinoma, and the postoperative pathological stage was T1-3N0-1M0. Thirty-four patients were followed up for 60 (40, 75) days after the operation. During the follow-up period, no complication or death occurred. In addition, neither recurrence nor metastasis was observed. Single-port laparoscopic and thoracoscopic McKeown esophagectomy for esophageal carcinoma is safe and feasible, with good short-term efficacy. Therefore we consider it an alternative minimally invasive surgery for esophageal cancer.

摘要

探讨单孔腹腔镜联合胸腔镜McKeown食管癌切除术的应用价值。进行一项回顾性研究,收集2020年8月至11月福建医科大学附属第一医院胸外科收治的34例食管癌患者的临床资料。所有患者,男性24例,女性10例,年龄43至75岁,平均(62±4)岁,均接受单孔腹腔镜联合胸腔镜McKeown食管癌切除术。在胸部,于左侧俯卧位采用传统四孔胸腔镜进行食管游离及纵隔淋巴结清扫。在腹部,采用单孔腹腔镜逆行三步法游离胃:首先,游离小网膜,用荷包针线悬吊左肝叶,之后游离胃左血管及淋巴结;其次,分离食管裂孔,切断贲门;最后,游离脾胃韧带完成上述步骤。观察手术时间、术中出血量、下床活动时间、术后引流管拔除时间、胸腔引流量、术后近期并发症、术后病理诊断、出院时间及随访结果。所有患者均成功实施单孔腹腔镜联合胸腔镜食管癌切除术,无一例中转开腹手术;患者手术时间为194至285(240±21)分钟,其中胸部手术时间为53至105(60±13)分钟,腹部手术时间为40至

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