Department of Gastroenterology, Peoples' Hospital of Dongying, Dongying 257091, Shandong Province, China.
Burn and Plastic Surgery, Shengli Oilfield Central Hospital, Dongying 257100, Shandong Province, China.
J Healthc Eng. 2022 Mar 27;2022:3409693. doi: 10.1155/2022/3409693. eCollection 2022.
To investigate the risk factors associated with reflux esophagitis in patients undergoing esophageal cancer surgery and to provide reference for the prevention and treatment of reflux esophagitis.
In the manner retrospective study, the data of 300 patients with esophageal cancer who received the surgical treatment in our hospital (January 2018-December 2020) were retrospectively reviewed. The 300 patients were divided into the occurrence group ( = 45) and nonoccurrence group ( = 255) depending on whether they had reflux esophagitis after surgery. The social demographic data and clinical data of the patients in the two groups were collected. These data were classified into the personal factors and surgical factors. The single-factor analysis method was adopted to analyze the effects of the personal and surgical factors on reflux esophagitis. The factors with statistically significant differences in the single-factor analysis were analyzed by logistic regression to verify the factors were the risk factors associated with reflux esophagitis in patients undergoing esophageal cancer surgery.
The differences in the bodyweight, body mass index (BMI), length of the resected esophagus, surgical approach, intraoperative blood loss, gastrointestinal decompression volume, and surgery time between the two groups were of statistical significance ( < 0.05). After being tested by the logistics multivariate analysis, length of the resected esophagus, whole stomach reconstruction, intraoperative blood loss, and surgery time were identified as the risk factors associated with reflux esophagitis in patients undergoing esophageal cancer surgery.
The length of the resected esophagus, whole stomach reconstruction, intraoperative blood loss, and surgery time were the risk factors associated with reflux esophagitis in patients undergoing esophageal cancer surgery. It is necessary to choose the appropriate surgical approach according to the patients' conditions in practice and to strengthen the prevention and treatment of reflux esophagitis.
探讨食管癌术后患者发生反流性食管炎的相关危险因素，为反流性食管炎的防治提供参考。
采用回顾性研究方法，回顾性分析 2018 年 1 月至 2020 年 12 月在我院接受手术治疗的 300 例食管癌患者的临床资料。将 300 例患者根据术后是否发生反流性食管炎分为发生组（45 例）和未发生组（255 例）。收集两组患者的社会人口学资料和临床资料，将资料分为个人因素和手术因素，采用单因素分析方法分析个人因素和手术因素对反流性食管炎的影响，对单因素分析差异有统计学意义的因素采用 logistic 回归分析进一步验证其是否为食管癌患者术后发生反流性食管炎的危险因素。
两组患者的体重、体质量指数（BMI）、切除食管长度、手术入路、术中出血量、胃肠减压量、手术时间比较，差异均有统计学意义（ < 0.05）。经 logistic 多因素分析检验，切除食管长度、全胃重建、术中出血量、手术时间为食管癌患者术后发生反流性食管炎的危险因素。
切除食管长度、全胃重建、术中出血量、手术时间是食管癌患者术后发生反流性食管炎的危险因素，在临床实践中应根据患者的具体情况选择合适的手术入路，并加强反流性食管炎的防治。
