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特发性脉络膜新生血管性 2 型黄斑部毛细血管扩张症所致全层黄斑裂孔的内界膜移植。

Internal limiting membrane graft in full-thickness macular hole secondary to macular telangiectasia type 2.

机构信息

Department of Ophthalmology, Antalya Education and Research Hospital, University of Health Sciences, Antalya, Turkey.

出版信息

J Fr Ophtalmol. 2021 Nov;44(9):1419-1424. doi: 10.1016/j.jfo.2021.05.003. Epub 2021 Jul 29.

Abstract

We present a case report of an autologous internal limiting membrane (ILM) graft transposition technique in a 60-years-old female patient who with a full-thickness macular hole (FTMH) secondary to idiopathic macular telangiectasia type 2 (MacTel type 2). To our knowledge, our case is the first report of ILM graft transposition to treat persistent FTMH secondary to MacTel type 2. MacTel type 2 is an acquired disease characterized by macular capillary abnormalities and retinal neurodegeneration. FTMH is an infrequent complication of MacTel type 2. Pars plana vitrectomy (PPV) with ILM peeling and gas endotamponade is the standard treatment of FTMH to help restore macular anatomy and visual function. The technique of autologous ILM graft transposition is a useful alternative to repair large, persistent macular holes that have failed to close with previous ILM peeling. In the present case, our patient with persistent FTMH secondary to MacTel type 2 after the previous standard macular hole surgery was admitted to our clinic. We performed 23-gauge PPV with extramacular ILM peeling and ILM graft transposition into the macular hole. 2 months after the surgery, her visual acuity had improved and anatomic closure of the FTMH was observed. In our opinion, ILM grafting might support reorganization of the retinal structure that has been affected by Muller cell degeneration.

摘要

我们报告了一例 60 岁女性自体内界膜(ILM)移植转位技术的病例,该患者因特发性黄斑毛细血管扩张症 2 型(MacTel 2 型)导致全层黄斑裂孔(FTMH)。据我们所知,我们的病例是首例报道 ILM 移植转位治疗 MacTel 2 型持续性 FTMH 的病例。MacTel 2 型是一种获得性疾病,其特征为黄斑毛细血管异常和视网膜神经退行性变。FTMH 是 MacTel 2 型的一种罕见并发症。裂孔源性黄斑病变的标准治疗方法是经睫状体平坦部玻璃体切除术(PPV)联合 ILM 剥除和硅油内填充,以帮助恢复黄斑解剖结构和视功能。自体 ILM 移植转位技术是修复先前 ILM 剥除后仍未闭合的大、持续性黄斑裂孔的一种有用的替代方法。在本病例中,我们的患者在先前的标准黄斑裂孔手术后仍存在 MacTel 2 型导致的持续性 FTMH,因此被收入我院。我们对其行 23G 微创玻璃体切除术,进行了黄斑外 ILM 剥除和 ILM 移植转位。术后 2 个月,她的视力得到改善,并且观察到 FTMH 解剖学上闭合。我们认为,ILM 移植可能有助于支持受 Muller 细胞变性影响的视网膜结构的重组。

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