Department of Neonatology, Lokmanya Tilak Municipal Medical College & General Hospital, Mumbai, India.
J Neonatal Perinatal Med. 2022;15(1):89-93. doi: 10.3233/NPM-210782.
Targeted neonatal echocardiography (Tn-Echo) is a non-invasive examination which may cause pain/discomfort and physiological instability in neonates, but there is little evidence for the same. We conducted this study to evaluate whether targeted neonatal echocardiography causes pain or physiological stress to newborn infants.
This cross-sectional study was conducted in a tertiary level NICU. Neonates undergoing targeted neonatal echocardiography were enrolled in this study. Pain was assessed using Premature Infant Pain Profile-Revised (PIPP-R) score before, during and after targeted neonatal echocardiography examination. Heart rate, oxygen saturation, perfusion index and blood pressure were also recorded at the same time points.
A total of 88 neonates were enrolled. Mean (SD) PIPP-R score during Tn-Echo was 8.18 (2.6) versus 3.60 (1.8) and 4.24 (2.0) before and after respectively (p value < 0.001). Heart rate and respiratory rate were significantly higher during targeted neonatal echocardiography; oxygen saturation and perfusion index were significantly lower during targeted neonatal echocardiography. Preterm infants had higher PIPP-R score compared to term neonates before, during and after the Tn-Echo [8.76 (2.4) versus 6.81 (2.4); p value < 0.001].
Targeted neonatal echocardiography causes significant pain/discomfort and physiological instability in neonates.
靶向新生儿超声心动图（Tn-Echo）是一种非侵入性检查，可能会导致新生儿疼痛/不适和生理不稳定，但相关证据很少。我们进行这项研究是为了评估靶向新生儿超声心动图是否会给新生儿带来疼痛或生理压力。
这是一项在三级 NICU 进行的横断面研究。纳入接受靶向新生儿超声心动图检查的新生儿。在检查前后使用早产儿疼痛评估工具修订版（PIPP-R）评分评估疼痛。同时记录心率、氧饱和度、灌注指数和血压。
共纳入 88 例新生儿。Tn-Echo 期间的平均（SD）PIPP-R 评分为 8.18（2.6），分别比检查前后的 3.60（1.8）和 4.24（2.0）高（p 值均<0.001）。在进行 Tn-Echo 期间，心率和呼吸频率显著升高；氧饱和度和灌注指数显著降低。与足月新生儿相比，早产儿在 Tn-Echo 前、中、后 PIPP-R 评分更高[8.76（2.4）比 6.81（2.4）；p 值均<0.001]。
靶向新生儿超声心动图会导致新生儿明显的疼痛/不适和生理不稳定。
