Davis Willam, Vavilin Ilan, Malhotra Nidhi
Internal Medicine, Georgetown University, Washington, DC, USA.
Gastroenterology, Washington Hospital Center, Washington, DC, USA.
Cureus. 2021 Jun 26;13(6):e15941. doi: 10.7759/cureus.15941. eCollection 2021 Jun.
Biologic therapy has revolutionized the management of chronic inflammatory diseases, including inflammatory bowel disease (IBD). Before the initiation of therapy, it is critical to rule out prior infection of chronic hepatitis B virus (HBV) and tuberculosis (TB). However, screening for human immunodeficiency virus (HIV) is not as routinely completed. We present a case of a 56-year-old male on ustekinumab for the management of Crohn's disease, found to have undiagnosed human immunodeficiency virus (HIV) with progression to acquired immunodeficiency syndrome (AIDS).
生物疗法彻底改变了包括炎症性肠病（IBD）在内的慢性炎症性疾病的治疗方式。在开始治疗之前，排除慢性乙型肝炎病毒（HBV）和结核病（TB）的既往感染至关重要。然而，人类免疫缺陷病毒（HIV）筛查并非常规进行。我们报告一例56岁男性，因使用乌司奴单抗治疗克罗恩病，被发现患有未确诊的人类免疫缺陷病毒（HIV），并进展为获得性免疫缺陷综合征（AIDS）。
