Ivey J Alexander, Cortese Cherise, Baird Bryce A, Thiel David D, Lyon Timothy D
Department of Urology, Mayo Clinic, Jacksonville, FL, USA.
Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL, USA.
Eur Urol Open Sci. 2021 May 10;29:10-14. doi: 10.1016/j.euros.2021.04.006. eCollection 2021 Jul.
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal malignancy that usually follows an indolent course. The few existing reports of metastatic MTSCC show poor response to systemic therapy. Here we describe the unusual case of a 39-yr-old male with MTSCC presenting as a large renal mass with bulky retroperitoneal lymphadenopathy managed with complete resection of disease. He has remained free of recurrence for 1 yr postoperatively. On the basis of the experience reported here, aggressive surgical resection of MTSCC with isolated nodal metastases may be considered for similar patients in the future given the historically poor response rates to systemic therapy.
黏液性小管状和梭形细胞癌（MTSCC）是一种罕见的肾脏恶性肿瘤，通常病程进展缓慢。现有的少数关于转移性MTSCC的报告显示，其对全身治疗反应不佳。在此，我们描述了一例不寻常的病例，一名39岁男性患有MTSCC，表现为巨大的肾脏肿块并伴有大量腹膜后淋巴结肿大，通过对病灶进行完整切除进行治疗。术后1年他一直未复发。基于此处报告的经验，鉴于既往对全身治疗的反应率较差，未来对于类似患者，可考虑对伴有孤立性淋巴结转移的MTSCC进行积极的手术切除。
