Serum bile-acids in liver cirrhosis: prognostic significance evidenced by a multivariate statistical model.

In order to evaluate the prognostic value of serum bile acids (SBA) in liver cirrhosis, we compared SBA levels with a theoretical expected survival length (ESL), computed on the ground of a previously proposed and validated multivariate statistical model. We demonstrated a strict correlation between SBA levels and ESL in subjects with liver cirrhosis by means of both standard linear correlation analysis and Logrank test. Our results account for a high predictive significance of SBA levels in liver cirrhosis, even in long term prognosis.