Jahoda M G, Pijpers L, Reuss A, Vosters R P, Wladimiroff J W, Sachs E S
Department of Obstetrics and Gynecology, Erasmus Universität Rotterdam, Niederlande.
Z Geburtshilfe Perinatol. 1987 Sep-Oct;191(5):199-201.
A total of 546 consecutive pregnancies was monitored following CVS to define the abortion risk. In 42 pregnancies an affected fetus was diagnosed and pregnancy subsequently terminated. In the remaining 504 pregnancies the fetal loss rate until 28 weeks of gestation was 26% (5.1%). Fetal loss rate was not influenced by the quantity of collected chorionic tissue. However in mothers with advanced age (greater than or equal to 36 years) the fetal loss rate before 16 weeks is related to the number of catheter insertions and increases from 3% after one insertion to 12.5% after three. It is concluded that maternal age is an additional risk to CVS if more than one catheter insertion is employed.
在绒毛取样（CVS）后，对总共546例连续妊娠进行了监测，以确定流产风险。在42例妊娠中，诊断出胎儿受影响，随后终止妊娠。在其余504例妊娠中，至妊娠28周的胎儿丢失率为26%（5.1%）。胎儿丢失率不受所采集绒毛组织数量的影响。然而，在高龄母亲（年龄大于或等于36岁）中，16周前的胎儿丢失率与导管插入次数有关，从一次插入后的3%增加到三次插入后的12.5%。得出的结论是，如果采用多次导管插入，母亲年龄是绒毛取样的一个额外风险因素。
