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[应用乙酰胆碱和阿米齐尔于视觉区域诱发兔皮层电位的空间同步性变化]

[Shifts in spatial synchronization of rabbit cortical potentials evoked by applying acetylcholine and amizil to the visual area].

作者信息

Kurova N S, Istrebtsov A I, Murav'ev I V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Sep-Oct;37(5):843-9.

PMID:3433926
Abstract

Acetylcholine solution application to the visual cortex of walking unrestrained rabbit led approximately in 5 minutes to a certain increase of the spatial synchronization of the cortical potentials at the small conditions, the the cortex, 24 EEG channels being used. Under the same conditions, the application of muscarinic antagonist amizil had an opposite more distinct effect. Endogenous cholinergic input increasing the spatial synchronization is supposed to play an important role in the formation of the spatiotemporal cortical potentials' organization necessary for the occurrence of complex behavioural acts.

摘要

将乙酰胆碱溶液应用于自由行走兔子的视觉皮层,在大约5分钟内,在小条件下,使用24个脑电图通道记录皮层电位时,皮层电位的空间同步性会有一定程度的增加。在相同条件下,应用毒蕈碱拮抗剂阿米齐尔则产生相反的、更明显的效果。内源性胆碱能输入增加空间同步性,被认为在形成复杂行为发生所必需的皮层电位时空组织中起着重要作用。

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