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[在皮层电位不同空间同步水平下对皮层进行电刺激时诱发反应的分布]

[Distribution of evoked responses to electrical stimulation of the cortex at different levels of spatial synchronization of cortical potentials].

作者信息

El'kina G A, Trush V D

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1980 Mar-Apr;30(2):360-7.

PMID:7386033
Abstract

In computer controlled experiments it was shown that the averaged cortical responses to direct electrical stimulation, recorded in rabbit's intact cortex or in a neuronally isolated cortical slab, depend on the level of EEG spatial synchronization in the prestimulation period. Latencies of the evoked potentials in both structures were smaller, and their amplitudes -- higher, if stimulation coincided with periods of the maximal synchronization of the background biopotentials, as compared to the same parameters of responses, obtained during the minimal synchronization of potentials. It is assumed that synchronization of the cortical potentials may be provided to a certain degree by processes of intracortical nature and that the increase in the cortical synchronization proper is accompanied by an improvement of the conditions in which the excitation is conducted over the cortex.

摘要

在计算机控制的实验中发现,在兔完整皮层或神经隔离的皮层片中记录到的对直接电刺激的平均皮层反应,取决于刺激前时期脑电图空间同步的水平。与在电位最小同步期间获得的相同反应参数相比,如果刺激与背景生物电位的最大同步期一致,则这两种结构中诱发电位的潜伏期较短,而其幅度较高。据推测,皮层电位的同步在一定程度上可能由皮层内性质的过程提供,并且皮层同步性本身的增加伴随着兴奋在皮层上传导的条件的改善。

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