Department of Nuclear Medicine, The University of Western Australia, Fiona Stanley Fremantle Hospitals, Murdoch, Australia.
Cancer Biother Radiopharm. 2021 Oct;36(8):617-623. doi: 10.1089/cbr.2021.0152. Epub 2021 Aug 2.
The landscape of nuclear oncology is rapidly changing. The advent of molecular radionuclide theranostics, multidisciplinary tumor board decision making, artificial intelligence and radiomics interpretation of diagnostic imaging, evolution of pharmacogenomics prediction of tumor response, and regulatory requirements for prospective individual dosimetry are just some of the elements which are broadening the essence of physician responsibility. The burgeoning knowledge base essential for mastering the emergent technologies, and their profound effect on moral philosophic aspects of provision of cancer care, are challenging. The new relationship of the theranostic nuclear physician with respect to shared care of the individual patient, particularly with regard to transparency, accountability, and responsibility for targeted radionuclide diagnosis and therapy of cancer, will be explored in this update.
核医学领域正在迅速发展。分子放射性核素治疗学的出现、多学科肿瘤委员会决策、人工智能和诊断成像的放射组学解释、肿瘤反应预测的药物基因组学演变,以及前瞻性个体剂量学的监管要求,这些只是拓宽医师责任本质的部分因素。新兴技术需要掌握的不断增长的知识库,以及它们对癌症护理提供的道德哲学方面的深远影响,都是具有挑战性的。本文将探讨治疗核医学医师与个体患者共同护理的新关系,特别是在靶向放射性核素诊断和癌症治疗的透明度、问责制和责任方面。