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幕上低级别胶质瘤的临床病程及手术结果

Clinical course and surgical results in supratentorial low-grade gliomas.

作者信息

Kotwica Z, Zawirski M, Papierz W, Jaskólski D

机构信息

Department of Neurosurgery, Medical Academy of Lódź.

出版信息

Zentralbl Neurochir. 1987;48(3):252-5.

PMID:3434025
Abstract

From 1968-1985 505 supratentorial primary brain tumors were operated on in Department of Neurosurgery of Medical Academy of Lódź, 49 of them (9%) were low-grade gliomas. Basing on WHO classification we found 29 fibrillary, 14 protoplasmatic, 1 pilocytic astrocytomas and 5 oligodendrogliomas. There were 19 men and 30 women. 70% of patients were 21-50 years old, and there were 5 children aged from 4 to 15 years. The initial symptoms were headache and epilepsy which occurred in 70% of astrocytomas and in all 5 cases of oligodendrogliomas. Only 2 patients presented symptoms of intracranial hypertension. The history of illness was shorter than 1 month in 10 patients (20%) and longer than 2 years in 20 (40%). 29 tumors were lobar with basal ganglia infiltration, 4 were located in central part of the brain and 16 were strictly lobar. These 16 tumors were removed totally and from 14 patients who survived operation 3 died of recurrence 3-5 years after surgery, but all the others are still alive, 7 of them longer than 5 years. In 19 cases tumor was removed partially, 4 patients died in postoperative period, 8 of recurrence 8 months to 4 years after surgery, but 7 is still alive, 4 longer than 5 years. In 14 cases only biopsy was performed, 7 patients died in first 12 months, 2 on the second and 1 one the fourth year after biopsy. 4 patients is alive longer than 1 year.

摘要

1968年至1985年期间,罗兹医学院神经外科对505例幕上原发性脑肿瘤进行了手术治疗,其中49例(9%)为低级别胶质瘤。根据世界卫生组织的分类,我们发现有29例纤维型、14例原浆型、1例毛细胞型星形细胞瘤和5例少突胶质细胞瘤。患者中男性19例,女性30例。70%的患者年龄在21至50岁之间,有5名儿童,年龄在4至15岁之间。初始症状为头痛和癫痫,70%的星形细胞瘤患者以及所有5例少突胶质细胞瘤患者均出现这些症状。只有2例患者表现出颅内高压症状。10例患者(20%)的病程短于1个月,20例患者(40%)的病程长于2年。29个肿瘤位于脑叶并伴有基底节浸润,4个位于脑中部,16个严格位于脑叶。这16个肿瘤全部切除,14例术后存活的患者中有3例在术后3至5年死于复发,但其他患者均存活,其中7例存活时间超过5年。19例患者肿瘤部分切除,4例患者在术后死亡,8例在术后8个月至4年死于复发,但7例仍存活,4例存活时间超过5年。14例患者仅进行了活检,7例患者在活检后的前12个月内死亡,2例在第二年死亡,1例在第四年死亡。4例患者存活时间超过1年。

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Clinical course and surgical results in supratentorial low-grade gliomas.幕上低级别胶质瘤的临床病程及手术结果
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