Jaskólsky D, Zawirski M, Papierz W, Kotwica Z
Department of Neurosurgery, Medical Academy of Lódź.
Zentralbl Neurochir. 1987;48(2):120-3.
43 cases of mixed gliomas (oligoastrocytomas) selected out of 505 supratentorial glial tumors were reviewed. 26 tumors were designated grade I and 17 as grade II. In 29 tumors two glial components occurred in about equal amounts whereas there was oligodendrocytes predominance in 11 cases and astrocytes preponderated only in 3 cases. 56% of the patients were male and 44% female. The mean age at the time of diagnosis was 45.6 years. There were 9 postoperative deaths and the result of surgery was poor in 6 cases. In the remaining 28 cases the immediate result was good or fair. There was a distinct tendency showed by the tumors with oligodendroglial cells predominance to involve the basal ganglia or contralateral hemisphere. As a corollary, these tumors had worse prognosis than the others. There was no difference in the result of surgery comparing grade I and II tumors. The average postoperative survival period was 47 months and the mean life span after the appearance of the first symptoms was 5.5 years. We failed to find the significance of divading tumors into grade I and II categories when applied to survival period.
在505例幕上神经胶质瘤中选取43例混合性胶质瘤（少突星形细胞瘤）进行回顾性研究。26例肿瘤被定为Ⅰ级，17例为Ⅱ级。29例肿瘤中两种神经胶质成分含量大致相等，11例以少突胶质细胞为主，仅3例以星形细胞为主。患者中男性占56%，女性占44%。诊断时的平均年龄为45.6岁。术后死亡9例，6例手术效果差。其余28例近期效果良好或尚可。以少突胶质细胞为主的肿瘤明显倾向于累及基底节或对侧半球。因此，这些肿瘤的预后比其他肿瘤差。Ⅰ级和Ⅱ级肿瘤的手术效果无差异。术后平均生存期为47个月，首次出现症状后的平均寿命为5.5年。我们未能发现将肿瘤分为Ⅰ级和Ⅱ级类别对生存期的意义。
