Gubin G D, Durov A M, Voronov O A, Komarov P I
Zh Evol Biokhim Fiziol. 1987 Sep-Oct;23(5):629-34.
It has been demonstrated that from the early stages of postnatal life up to adult age, gradual development of circadian amplitudes invariably takes place which may lead up to a complete absence of the diurnal rhythm in senile organisms. These changes are observed at various levels of organization of homeostatic systems (from cellular to organismic ones). A discussion is made of a possibility of evaluation of the level of adaptability and reliability of biological systems, as well as of their functional optimum via the analysis of circadian organization in ontogenesis, including gerontological problems (differentiation into age periods, biological age).
已经证明,从出生后早期到成年期,昼夜节律振幅会逐渐发展,这可能导致老年生物体内昼夜节律完全消失。这些变化在稳态系统的各个组织层次(从细胞到生物体)都能观察到。本文讨论了通过分析个体发育过程中的昼夜节律组织,包括老年学问题(年龄阶段的分化、生物学年龄),来评估生物系统适应性和可靠性水平以及其功能最优性的可能性。