Eye Center of Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Hunan Key Laboratory of Ophthalmology, Changsha, 410008, Hunan, China.
BMC Ophthalmol. 2021 Aug 2;21(1):292. doi: 10.1186/s12886-021-02048-5.
To compare the correction effect and optical quality after small-incision lenticule extraction (SMILE) and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia.
51 high myopia eyes after SMILE and 49 high myopia eyes after FS-LASIK were enrolled and divided into two groups retrospectively. The OQAS and iTrace analyzer were used for optical quality inspection. Between the two groups the spherical equivalent (SE), astigmatism, uncorrected distant visual acuity (UDVA), strehl ratio (SR), modulation transfer function cutoff frequency (MTF cutoff), objective scatter index (OSI) and wavefront aberrations were analyzed and compared before surgery and at 1, 6 and 12 months after surgery.
After the operation: (1) SE and astigmatism declined and UDVA increased significantly in both groups, and UDVA was better after SMILE than FS-LASIK. (2) SR and MTF cutoff reduced and OSI increased significantly after SMILE and FS-LASIK. SR and MTF cutoff were significantly higher after SMILE than FS-LASIK. OSI was significantly lower after SMILE than FS-LASIK. (3) The total wavefront aberration, total low-order wavefront aberration, defocus and astigmatism aberration as well as trefoil aberration reduced significantly in both groups. The total high-order wavefront aberration increased significantly after FS-LASIK. The spherical and coma aberration increased significantly in both groups. The total high-order wavefront aberration and coma aberration at 1 month were higher after FS-LASIK than SMILE.
The optical quality descended after SMILE and FS-LASIK. SMILE was superior to FS-LASIK at the correction effect and optical quality for high myopia. The combination of OQAS and iTrace analyzer is a valuable complementary measurement in evaluating the optical quality after the refractive surgery.
This is a retrospective study. This research was approved by the ethics committee of Xiangya Hospital and the IRB approval number is 201612074.
比较小切口角膜基质透镜取出术（SMILE）和飞秒激光辅助准分子激光原位角膜磨镶术（FS-LASIK）治疗高度近视的矫正效果和光学生物质量。
回顾性纳入 SMILE 术后 51 只眼和 FS-LASIK 术后 49 只眼的高度近视患者，分为两组。采用 OQAS 和 iTrace 分析仪进行光学质量检查。比较两组患者术前及术后 1、6、12 个月的等效球镜（SE）、散光、未矫正远视力（UDVA）、斯特列尔比（SR）、调制传递函数截止频率（MTF cutoff）、客观散射指数（OSI）和波前像差。
术后：（1）两组 SE 和散光均下降，UDVA 均显著提高，SMILE 组优于 FS-LASIK 组。（2）SMILE 和 FS-LASIK 术后 SR 和 MTF cutoff 均显著降低，OSI 均显著升高，SMILE 组 SR 和 MTF cutoff 均显著高于 FS-LASIK 组，OSI 显著低于 FS-LASIK 组。（3）两组总波前像差、总低阶像差、离焦和散光像差以及彗差均显著降低，FS-LASIK 组总高阶像差显著增加。两组球差和彗差均显著增加，FS-LASIK 组术后 1 个月总高阶像差和彗差高于 SMILE 组。
SMILE 和 FS-LASIK 术后光学生物质量下降。SMILE 在矫正效果和光学生物质量方面优于 FS-LASIK 治疗高度近视。OQAS 和 iTrace 分析仪的结合是评估屈光手术后光学生物质量的一种有价值的补充测量方法。
这是一项回顾性研究。本研究经湘雅医院伦理委员会批准，注册号为 201612074。
