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眼科手术中抗血小板和抗凝药物的围手术期管理更新。

Update on the perioperative management of antiplatelets and anticoagulants in ophthalmic surgery.

机构信息

Servicio de Oftalmología, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain.

Servicio de Oftalmología, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain.

出版信息

Arch Soc Esp Oftalmol (Engl Ed). 2021 Aug;96(8):422-429. doi: 10.1016/j.oftale.2020.11.001. Epub 2021 Mar 5.

DOI:10.1016/j.oftale.2020.11.001
PMID:34340780
Abstract

INTRODUCTION

Anti-thrombotic drugs (antiplatelets and anticoagulants) are widely used for different clinical reasons. This means that there are an increasing number of patients undergoing elective ophthalmic surgery that are being treated with these drugs. A better knowledge of their implications and their peri-operative use may help to prevent surgical and secondary adverse events. There is often no firm recommendation on how to manage certain drugs in certain surgeries.

OBJECTIVE

To review the recommendations in the scientific literature as regards managing anti-thrombotic agents during the peri-operative period of ophthalmic surgery.

MATERIAL AND METHODS

A review was made of the relevant guidelines and studies using an antiplatelet and anticoagulant drugs approach for cataract, vitreo-retinal, glaucoma, oculoplastic, and strabismus surgeries.

RESULTS

Recommendations about whether to continue or discontinue anti-thrombotic drugs in the peri-operative period of different ophthalmic surgical fields are presented.

CONCLUSIONS

There are only firm recommendations of maintaining anti-thrombotic drugs as regards cataract surgery using phacoemulsification with topical anaesthesia. In other surgical fields, ophthalmologists should balance the risk of thromboembolic events and risks of haemorrhagic complications in order to carry out a proper management. A multi-disciplinary approach is recommended for complex cases. Additional studies should be performed to better characterise the peri-operative use of anti-thrombotic agents in order to prepare clinical guidelines for ophthalmic surgery.

摘要

简介

抗血栓药物(抗血小板和抗凝剂)因不同的临床原因被广泛应用。这意味着越来越多正在接受择期眼科手术的患者正在接受这些药物的治疗。更好地了解这些药物的影响及其围手术期的使用方法,可能有助于预防手术和继发性不良事件。对于某些手术中如何管理某些药物,通常没有明确的建议。

目的

回顾科学文献中关于眼科手术围手术期管理抗血栓药物的建议。

材料和方法

对有关指南和研究进行了综述,采用抗血小板和抗凝药物方法治疗白内障、玻璃体视网膜、青光眼、眼整形和斜视手术。

结果

提出了不同眼科手术领域围手术期是否继续或停止抗血栓药物的建议。

结论

只有在使用局部麻醉的超声乳化白内障手术中,才强烈建议继续使用抗血栓药物。在其他手术领域,眼科医生应权衡血栓栓塞事件的风险和出血并发症的风险,以便进行适当的管理。对于复杂病例,建议采用多学科方法。应进行更多的研究,以更好地描述抗血栓药物在围手术期的使用情况,为眼科手术制定临床指南。

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