IRYCIS, Ophthalmology, Hospital Ramón y Cajal, Madrid, Spain.
IRYCIS, Ophthalmology, Hospital Ramón y Cajal, Madrid, Spain
Br J Ophthalmol. 2023 Jan;107(1):6-11. doi: 10.1136/bjophthalmol-2021-319666. Epub 2021 Aug 2.
To define and quantify the upper lid contour by adapting Bézier curves with a newly developed software in normal subjects, assessing their reliability.
Fifty eyes of 50 healthy patients with no ocular pathology were included in this study from October 2020 to November 2020. All measurements were performed on Bézier curves adjusted to the upper lid contour. An original software was used to measure the radial and vertical midpupil-to-lid margin distances (MPLD), temporal-to-nasal (T/N) ratios, contour peak location and grade of superposition (GS) and asymmetry (GA) indexes. We calculated differences in the variables measured regarding age, gender or the side of the eye being assessed.
The mean Bézier curve showed an excellent level of inter-rater reliability (intraclass correlation coefficient of 0.99). The median GS index of each eyelid to the mean Bézier curve was 95.4%, 8.5 IQR, and the median GA index was 3%, 3.4 IQR. The mean contour peak location was -0.35 mm, SD 0.45. Overall, the mean central MPLD was 4.1 mm, SD 0.6. No significant differences were found between male and female patients in variables derived from Bézier curves.
Bézier curves may become a very useful tool for the assessment of upper lid contour, contour peak and symmetry. GS and GA indexes, along with the T/N area ratio are potential outcomes for this purpose. All current variables can be obtained just from one single Bézier curve measurement. Our results offer an in-depth exhaustive description of these variables and their distribution in the normal population.
通过使用新开发的软件,采用贝塞尔曲线来定义和量化正常受试者的上睑轮廓,并评估其可靠性。
本研究纳入了 2020 年 10 月至 2020 年 11 月期间 50 名无眼部疾病的健康患者的 50 只眼。所有测量均在上睑轮廓的贝塞尔曲线上进行。使用原始软件测量瞳孔至睑缘的水平和垂直中值(MPLD)、颞侧到鼻侧(T/N)比值、轮廓峰的位置以及重叠度(GS)和不对称度(GA)指数。我们计算了与年龄、性别或评估眼侧相关的变量测量值的差异。
平均贝塞尔曲线的组内相关性系数为 0.99,表明其具有极好的可靠性。每只眼睑相对于平均贝塞尔曲线的 GS 指数中位数为 95.4%,四分位距(IQR)为 8.5%;GA 指数中位数为 3%,IQR 为 3.4%。平均轮廓峰的位置为-0.35mm,标准差(SD)为 0.45mm。总体而言,中央 MPLD 的平均值为 4.1mm,SD 为 0.6mm。在贝塞尔曲线得出的变量方面,男性和女性患者之间无显著差异。
贝塞尔曲线可能成为评估上睑轮廓、轮廓峰和对称性的非常有用的工具。GS 和 GA 指数以及 T/N 面积比可能是为此目的的潜在结果。目前所有的变量都可以仅通过一次贝塞尔曲线测量获得。我们的结果提供了这些变量及其在正常人群中的分布的详细描述。