Shin Da Young, Cho Won-Kyung, Paik Ji-Sun, Yang Suk-Woo
Department of Ophthalmology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Ophthalmology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
PLoS One. 2025 Jun 3;20(6):e0316714. doi: 10.1371/journal.pone.0316714. eCollection 2025.
To define and quantify the upper eyelid contour of normal Asian adults using a software program utilizing Bézier curves.
Eighty eyes of 80 healthy Korean subjects were included in this study. The Bézier curve tool of Image J software was used to extract the upper eyelid contours. The x and y coordinate values of the four points of the Bézier curve were analyzed using graphical analysis software in Matlab. Various parameters were measured automatically using a custom-written software algorithm.
The Bézier curves showed an excellent level of inter-rater reliability (intraclass correlation coefficient of 0.97 for absolute agreement, two-way random effects model, 95% CI 0.94 to 0.98). The Bézier curve for Asians was drawn from the medial palpebral commissure to the lateral canthus. The eye width was 24.8[Formula: see text]1.8 mm in women and 25.3[Formula: see text]2.0 mm in men. The contour peak was located at 1.7[Formula: see text]1.0 mm temporally from the pupil center in women and 1.5[Formula: see text]1.3 mm in men, and the height was 4.7[Formula: see text]0.7 mm in women and 3.8[Formula: see text]0.9 mm in men. The palpebral fissure obliquity (angle of the line connecting the medial canthal end to the lateral canthal end) was 9.98[Formula: see text]3.07° in women and 7.52[Formula: see text]2.89° in men.
The upper eyelid contour was measured simply and efficiently using a Bézier curves function. The main features of Asian upper eyelid contour are that the inner part of the medial canthus is covered by the eyelids, and the lateral endpoint is located higher than the medial endpoint.
使用贝塞尔曲线的软件程序定义并量化正常亚洲成年人的上睑轮廓。
本研究纳入80名健康韩国受试者的80只眼睛。使用Image J软件的贝塞尔曲线工具提取上睑轮廓。使用Matlab中的图形分析软件分析贝塞尔曲线四个点的x和y坐标值。使用自定义编写的软件算法自动测量各种参数。
贝塞尔曲线显示出极好的评分者间信度水平（绝对一致性的组内相关系数为0.97，双向随机效应模型，95%置信区间为0.94至0.98）。亚洲人的贝塞尔曲线是从睑内侧联合至外眦绘制的。女性眼宽为24.8[公式：见正文]1.8毫米，男性为25.3[公式：见正文]2.0毫米。轮廓峰值在女性中位于瞳孔中心颞侧1.7[公式：见正文]1.0毫米处，男性为1.5[公式：见正文]1.3毫米处，高度在女性中为4.7[公式：见正文]0.7毫米，男性为3.8[公式：见正文]0.9毫米。睑裂倾斜度（连接内眦端至外眦端的线的角度）在女性中为9.98[公式：见正文]3.07°，男性为7.52[公式：见正文]2.89°。
使用贝塞尔曲线功能可简单有效地测量上睑轮廓。亚洲人上睑轮廓的主要特征是内眦内侧部分被眼睑覆盖，外侧端点高于内侧端点。
