Department of Ophthalmology, Division of Oculoplastic, University of São Paulo Medical School, 255 Eneas Aguiar Street Office 4079, São Paulo, Zipcode, 05403000, Brazil.
Department of Medicine, Division of Dermatology, Mato Grosso State University, Tancredo Neves Avenue 1095, Cáceres, Mato Grosso, 78200000, Brazil.
Aesthetic Plast Surg. 2022 Feb;46(1):385-394. doi: 10.1007/s00266-021-02483-1. Epub 2021 Aug 2.
Currently, botulinum toxin (BoNT) injections are the most commonly performed non-invasive procedure for rejuvenation on the upper face. The therapeutic use of botulinum toxin has generally been safe and well tolerated. Adverse effects are considered mild, transient, and self-limited. However, as with all other injectable procedures, this one is also susceptible to adverse events and complications. When the safety zones are respected, the chance of any of these complications is practically null. Thus, this review aims to describe the main complications of treatment with BoNT on the upper face and to present a practical guide based on current evidence on how to avoid them.
The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles.
The main complications secondary to BoNT injections on the upper face are: ptosis of eyelid or eyebrow, eyebrow asymmetry, diplopia, Lakeophthalmos, Palpebral ectropion, and prominence of the palpebral bags. To avoid such complications, it is necessary to have knowledge of the anatomy of this region and adequate and individualized planning based on the existing patterns of the frontalis muscle, glabella, and crow's feet. This review presents the specificities of each of these regions and practical suggestions to obtain satisfactory results, avoiding complications.
Particularly on the upper face treatment with BoNT offers predictable results, has few adverse effects, and is associated with high patient satisfaction. However, it is suggested that the commented parameters and safety areas be incorporated into daily practice so that the possibilities of complications are minimized as much as possible.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
目前,肉毒毒素(BoNT)注射是用于面部上部年轻化的最常见的非侵入性程序。肉毒毒素的治疗用途通常是安全且耐受良好的。不良反应被认为是轻微的、短暂的和自限性的。然而,与所有其他注射程序一样,这种程序也容易发生不良事件和并发症。当安全区域得到尊重时,这些并发症发生的可能性实际上为零。因此,本综述旨在描述面部上部 BoNT 治疗的主要并发症,并根据当前关于如何避免这些并发症的证据,提供实用指南。
文献研究考虑了已发表的期刊文章(临床试验或科学综述)。通过搜索电子数据库(MEDLINE 和 PubMed)和各自文章的参考文献来确定研究。
面部上部 BoNT 注射的主要并发症有:眼睑或眉毛下垂、眉毛不对称、复视、眼睑闭合不全、眼睑外翻和眼袋突出。为避免此类并发症,需要了解该区域的解剖结构,并根据额肌、眉间和鱼尾纹的现有模式进行充分和个体化的规划。本综述介绍了这些区域的具体情况,并提供了实用建议,以获得满意的效果,避免并发症。
特别是在面部上部,BoNT 治疗可提供可预测的结果,不良反应少,患者满意度高。然而,建议将评论的参数和安全区域纳入日常实践,以尽可能减少并发症的可能性。
证据水平 III:本杂志要求作者为每篇文章分配一个证据水平。有关这些循证医学评级的完整描述,请参考目录或在线作者指南 www.springer.com/00266 。