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猫气道平滑肌对组胺反应性的年龄和体重依赖性变化。

Age- and body-weight-dependent changes in the reactivity to histamine of the airways smooth muscles in cats.

作者信息

Visnovský P, Bánovcin P, Korpás J

机构信息

Department of Pathophysiology and Pharmacology, Faculty of Medicine, Comenius University, Martin, Czechoslovakia.

出版信息

Acta Physiol Hung. 1987;70(2-3):201-6.

PMID:3434299
Abstract

The relation between age and body weight and the reactivity to histamine of the tracheopulmonary contractile tissues was studied in cats in vitro. The reactivity of the tracheal smooth muscle to histamine decreased with increasing age from the newborn (100%) and one-month-old (57%) to the adult (0%) cat, whereas the amplitudes of contractions of lung strips increased. The amplitudes in adult animals also increased moderately with increasing body weight.

摘要

在体外对猫进行研究,以探讨年龄与体重之间的关系以及气管肺收缩组织对组胺的反应性。气管平滑肌对组胺的反应性随着年龄的增长而降低,从新生猫(100%)、1月龄猫(57%)到成年猫(0%),而肺条的收缩幅度则增加。成年动物的收缩幅度也随着体重的增加而适度增加。

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