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实验性诱导气道炎症对猫肺实质条带对组胺和乙酰胆碱反应性的影响。

Influence of experimentally induced airway inflammation on the reactivity of cat lung parenchymal strips to histamine and acetylcholine.

作者信息

Bánovcin P, Visnovský P, Hanácek J, Korpás J

出版信息

Respiration. 1987;51(1):1-9. doi: 10.1159/000195159.

DOI:10.1159/000195159
PMID:3563118
Abstract

The reactivity of cat lung parenchymal strips to histamine and acetylcholine in vitro was studied at various stages of inflammation of the airways induced experimentally by the intratracheal administration of turpentine oil or Staphylococcus aureus, both in aerosol form. With histamine, the contractile responses of the lung strips were enhanced depending on the stage of turpentine oil inflammation. Similarly, the lung strips responded more to histamine in the staphylococcal inflammation. The reactivity of the lung strips to acetylcholine remained mainly unaffected by either type of inflammation.

摘要

通过气管内给予气雾剂形式的松节油或金黄色葡萄球菌,在实验诱导的气道炎症的各个阶段,研究了猫肺实质条带在体外对组胺和乙酰胆碱的反应性。对于组胺,肺条带的收缩反应根据松节油炎症的阶段而增强。同样,在葡萄球菌性炎症中,肺条带对组胺的反应更强。肺条带对乙酰胆碱的反应性主要不受任何一种炎症类型的影响。

相似文献

1
Influence of experimentally induced airway inflammation on the reactivity of cat lung parenchymal strips to histamine and acetylcholine.实验性诱导气道炎症对猫肺实质条带对组胺和乙酰胆碱反应性的影响。
Respiration. 1987;51(1):1-9. doi: 10.1159/000195159.
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Pharmacological analysis of reactivity changes in airways due to acute inflammation in cats.猫急性炎症引起气道反应性变化的药理学分析
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Reactivity of cat tracheal smooth muscle to histamine under conditions of experimentally induced inflammation.
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Effects of meconium on airway reactivity to histamine and acetylcholine in vitro.胎粪对体外气道对组胺和乙酰胆碱反应性的影响。
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Effect of histamine on the airway smooth muscle of cats under control and inflammatory conditions.组胺对正常及炎症状态下猫气道平滑肌的作用。
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J Clin Invest. 1978 Jun;61(6):1441-7. doi: 10.1172/JCI109063.
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Age- and body-weight-dependent changes in the reactivity to histamine of the airways smooth muscles in cats.猫气道平滑肌对组胺反应性的年龄和体重依赖性变化。
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Effects of atropine, acetylsalicylic acid, FPL 55712, and phentolamine on increased histamine responsiveness of cat lung strips under conditions of airway inflammation.在气道炎症条件下,阿托品、乙酰水杨酸、FPL 55712和酚妥拉明对猫肺条组胺反应性增加的影响。
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Changes in airway sensitivity to histamine are not necessarily paralleled by changed sensitivity to acetylcholine.气道对组胺敏感性的变化不一定与对乙酰胆碱敏感性的变化平行。
Agents Actions Suppl. 1991;34:257-66.

引用本文的文献

1
Effect of histamine on the airway smooth muscle of cats under control and inflammatory conditions.组胺对正常及炎症状态下猫气道平滑肌的作用。
Agents Actions. 1988 Apr;23(3-4):314-6. doi: 10.1007/BF02142574.