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COVID-19 对美国 717103 例成年心脏手术的影响。

The Effect of COVID-19 on Adult Cardiac Surgery in the United States in 717 103 Patients.

机构信息

Department of Surgery, Division of Cardiothoracic Surgery, University of California San Francisco, San Francisco, California.

Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, Georgia.

出版信息

Ann Thorac Surg. 2022 Mar;113(3):738-746. doi: 10.1016/j.athoracsur.2021.07.015. Epub 2021 Jul 31.

Abstract

BACKGROUND

COVID-19 has changed the world as we know it, and the United States continues to accumulate the largest number of COVID-related deaths worldwide. There exists a paucity of data regarding the effect of COVID-19 on adult cardiac surgery trends and outcomes on regional and national levels.

METHODS

The Society of Thoracic Surgeons Adult Cardiac Surgery Database was queried from January 1, 2018, to June 30, 2020. The Johns Hopkins COVID-19 database was queried from February 1, 2020, to January 1, 2021. Surgical and COVID-19 volumes, trends, and outcomes were analyzed on a national and regional level. Observed-to-expected ratios were used to analyze risk-adjustable mortality.

RESULTS

The study analyzed 717 103 adult cardiac surgery patients and more than 20 million COVID-19 patients. Nationally, there was a 52.7% reduction in adult cardiac surgery volume and a 65.5% reduction in elective cases. The Mid-Atlantic region was most affected by the first COVID-19 surge, with 69.7% reduction in overall case volume and 80.0% reduction in elective cases. In the Mid-Atlantic and New England regions, the observed-to-expected mortality for isolated coronary bypass increased as much as 1.48 times (148% increase) pre-COVID rates. After the first COVID-19 surge, nationwide cardiac surgical case volumes did not return to baseline, indicating a COVID-19-associated deficit of cardiac surgery patients.

CONCLUSIONS

This large analysis of COVID-19-related impact on adult cardiac surgery volume, trends, and outcomes found that during the pandemic, cardiac surgery volume suffered dramatically, particularly in the Mid-Atlantic and New England regions during the first COVID-19 surge, with a concurrent increase in observed-to-expected 30-day mortality.

摘要

背景

新冠疫情改变了我们的世界,美国继续累积着全球与新冠相关的最多死亡人数。关于新冠疫情对成人心脏手术趋势和结果的影响,在区域和国家层面上的数据非常匮乏。

方法

从 2018 年 1 月 1 日至 2020 年 6 月 30 日,我们查询了胸外科医师学会成人心脏手术数据库。从 2020 年 2 月 1 日至 2021 年 1 月 1 日,我们查询了约翰霍普金斯新冠疫情数据库。我们在国家和区域层面分析了手术和新冠疫情量、趋势和结果。我们使用观察到的与预期的比值来分析可调整风险的死亡率。

结果

这项研究分析了 717103 例成人心脏手术患者和 2000 多万例新冠患者。在全国范围内,成人心脏手术量减少了 52.7%,择期手术减少了 65.5%。大西洋中部地区受第一波新冠疫情的影响最大,总病例量减少了 69.7%,择期手术减少了 80.0%。在大西洋中部和新英格兰地区,单纯冠状动脉旁路移植术的观察到的与预期的死亡率增加了 1.48 倍(增加了 148%),超过了新冠前的水平。在第一波新冠疫情过后,全国范围内的心脏手术病例量并未恢复到基线水平,这表明新冠疫情导致了心脏手术患者的短缺。

结论

这项关于新冠疫情对成人心脏手术量、趋势和结果的影响的大型分析发现,在大流行期间,心脏手术量急剧下降,特别是在第一波新冠疫情期间的大西洋中部和新英格兰地区,同时观察到的 30 天死亡率与预期相比有所增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b87/8325556/20a4511de3b7/gr1_lrg.jpg

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