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作者信息

August Dietrich, Götz Veronika, Stete Katarina

机构信息

Klinik für Innere Medizin II, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg.

出版信息

Dtsch Med Wochenschr. 2021 Aug;146(15):972-977. doi: 10.1055/a-1447-9253. Epub 2021 Aug 3.

Abstract

Some patients complain of persisting symptoms after acute COVID-19. There is no universal definition yet for these post-acute sequelae, also termed Long COVID. Although their prevalence remains to be established, a delayed recovery seems to be more common than after other acute infectious diseases. Common complaints include fatigue with exercise intolerance, dyspnea on exertion, chest pain, and neuropsychiatric symptoms. Female sex, comorbidities, and severity of the acute disease have been identified as risk factors for persisting symptoms. It is, however, important to highlight that they are not limited to patients after severe COVID-19. Whilst their pathogenesis and prognosis is largely unknown, diagnostic evaluation should focus on exclusion of objective organ dysfunctions. Due to the variable presentation, management is interdisciplinary and may include physiotherapy, rehabilitation programmes, and psychological support. This article aims to summarize the current - limited - evidence on persisting symptoms after COVID-19.

摘要

一些患者在急性新冠病毒感染后仍有症状。对于这些急性后遗症(也称为“长新冠”),目前尚无统一的定义。尽管其患病率仍有待确定,但延迟康复似乎比其他急性传染病后更为常见。常见症状包括运动不耐受性疲劳、劳力性呼吸困难、胸痛和神经精神症状。女性、合并症和急性疾病的严重程度已被确定为持续症状的风险因素。然而,必须强调的是,这些症状并不局限于重症新冠患者。虽然其发病机制和预后在很大程度上尚不清楚,但诊断评估应侧重于排除客观器官功能障碍。由于表现多样,管理需要多学科协作,可能包括物理治疗、康复计划和心理支持。本文旨在总结目前关于新冠病毒感染后持续症状的有限证据。

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