Patel Zalak, Meadows Lukas, Kehinde Temitope, White Jennifer Koay
Department of Radiology, West Virginia University, Morgantown, WV.
Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University, Morgantown, WV.
Radiol Case Rep. 2021 Jul 15;16(9):2680-2686. doi: 10.1016/j.radcr.2021.06.045. eCollection 2021 Sep.
Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor with metastatic potential and estimated prevalence of less than one case per million. Among the musculoskeletal system, the long bones are commonly involved with approximately half patients experiencing multicentric involvement. Clinical course of EHE is often variable and nonspecific. Poorly demarcated osteolytic lesions are most commonly seen radiologically. Diagnostic confirmation is usually obtained by biopsy and histopathological exam, including immunostaining for endothelial markers. We present a rare case of unicentric EHE involving the calcaneum. Our patient had an indolent course of disease after surgical resection and no recurrence in seven years on clinical and radiological surveillance.
上皮样血管内皮瘤(EHE)是一种罕见的具有转移潜能的血管肿瘤,估计患病率低于百万分之一。在肌肉骨骼系统中,长骨常受累,约半数患者有多中心受累。EHE的临床病程通常多变且无特异性。影像学上最常见界限不清的溶骨性病变。通常通过活检和组织病理学检查确诊,包括内皮标志物的免疫染色。我们报告一例罕见的单中心EHE累及跟骨的病例。我们的患者手术切除后病程进展缓慢,临床和影像学随访7年无复发。