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水合作用在肾脏健康和疾病中的环境作用。

The Environmental Role of Hydration in Kidney Health and Disease.

机构信息

Research Department, Fundação Pró-Rim, Joinville, Brazil.

School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.

出版信息

Contrib Nephrol. 2021;199:252-265. doi: 10.1159/000517712. Epub 2021 Aug 4.

DOI:10.1159/000517712
PMID:34348261
Abstract

Clinical Background: Hydration status, which is influenced by environment and self-behavior is associated with kidney health and disease. Epidemiology: Lack of safe water, sanitation, and high temperatures are environmental issues that affect a significant part of the worldwide population. Occupational factors that discourage proper hydration, as well as low water intake in favorable environment conditions, are also highly prevalent. As a consequence, inadequate water intake can lead to several kidney problems ranging from uncomplicated urinary tract infections to kidney stones, acute kidney injury, and chronic disorders with high mortality rates. Challenges: Increasing water intake is an individual effort when self-behavior is the main reason for inadequate hydration status. When the environment is an obstacle, it might require complex changes in a concerted multidisciplinary effort from employers, health authorities, researchers, and governments. Prevention and Treatment: Strategies can be implemented at global, local, and individual levels. Global efforts include actions to decrease poverty and climate change consequences, while increasing access to safe water and sanitation. Local actions can improve working conditions and access to water and toilets to workers. At an individual level, self-monitoring through regular observation of thirst sensation, acute weight loss, urine frequency, and urine color are recommended tools to monitor hydration status.

摘要

临床背景

水合状态受环境和自身行为的影响,与肾脏健康和疾病有关。

流行病学

缺乏安全用水、环境卫生和高温是影响全球很大一部分人口的环境问题。职业因素也会抑制适当的水合作用,而在有利的环境条件下水的摄入量低也很常见。因此,水合作用不足会导致多种肾脏问题,从简单的尿路感染到肾结石、急性肾损伤和高死亡率的慢性疾病。

挑战

当自身行为是水合状态不足的主要原因时,增加水的摄入量是个人的努力。当环境成为障碍时,可能需要雇主、卫生当局、研究人员和政府共同做出复杂的改变。

预防和治疗

可以在全球、地方和个人层面实施策略。全球努力包括采取行动减少贫困和气候变化的影响,同时增加安全用水和卫生设施的获取。地方行动可以改善工人的工作条件和获取水和厕所的途径。在个人层面上,通过定期观察口渴感、急性体重减轻、尿频率和尿液颜色来自我监测,是监测水合状态的推荐工具。

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