Skinhøj P, Aldershvile J, Hardt F
Acta Pathol Microbiol Scand C. 1977 Dec;85C(6):401-5. doi: 10.1111/j.1699-0463.1977.tb03661.x.
Hepatitis B surface antigen (HBsAg), the corresponding antibody (anti-HBs), the antibody to hepatitis B core antigen (anti-HBc), and the cellular immune response to purified HBsAg (leucocyte migration inhibition test: LMT-HBsAg) were determined in 19 staff members, 11 long-term haemodialysis patients, and 22 renal transplant patients in a haemodialysis-renal transplantation unit. Past or present infection, as expressed by the presence of circulating anti-HBs or HBsAg, was found in 30 cases (58 per cent) (11 staff members, six dialysis patients and 13 transplant patients). Anti-HBc was found in all the ten HBsAg positive cases--all patients--and in 15 out of 20 anti-HBs positive cases. Four staff members and seven patients had positive LMT-HBsAg; of these only one patient had HBsAg, whereas seven cases had anti-HBs. Neither the antibody determination nor the leucocyte migration inhibition assay disclosed any significant difference between patients and staff which could explain the different course of the hepatitis B virus infection in the two groups.
对一家血液透析-肾移植单位的19名工作人员、11名长期血液透析患者和22名肾移植患者，检测了乙肝表面抗原（HBsAg）、相应抗体（抗-HBs）、乙肝核心抗原抗体（抗-HBc）以及对纯化HBsAg的细胞免疫反应（白细胞游走抑制试验：LMT-HBsAg）。根据循环抗-HBs或HBsAg的存在情况判断，30例（58%）（11名工作人员、6名透析患者和13名移植患者）存在既往或现感染。所有10例HBsAg阳性病例（全部为患者）均检测到抗-HBc，20例抗-HBs阳性病例中有15例检测到抗-HBc。4名工作人员和7名患者LMT-HBsAg呈阳性；其中仅1例患者有HBsAg，而7例有抗-HBs。抗体检测和白细胞游走抑制试验均未显示患者和工作人员之间存在任何显著差异，无法解释两组中乙肝病毒感染的不同病程。
