Effects of all-trans retinoic acid on the morphology of human epidermal cells in vitro.
作者信息
Konohana I, Hashimoto T, Dykes P J, Marks R
机构信息
Department of Medicine (Dermatology), University of Wales College of Medicine, Health Park, Cardiff, UK.
出版信息
Arch Dermatol Res. 1987;279(7):459-64. doi: 10.1007/BF00412592.
PMID:3435175
Abstract
The effects of all-trans retinoic acid on human epidermal cell cultures were studied using ultrastructural techniques. Differentiation and stratification were reduced in retinoic acid treated epidermal cells. Treated cells developed a rounded appearance and seemed to contain more granules and vacuoles than usual. Desmosomes were not found in treated cells.
摘要
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