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Effects of all-trans retinoic acid on the morphology of human epidermal cells in vitro.

作者信息

Konohana I, Hashimoto T, Dykes P J, Marks R

机构信息

Department of Medicine (Dermatology), University of Wales College of Medicine, Health Park, Cardiff, UK.

出版信息

Arch Dermatol Res. 1987;279(7):459-64. doi: 10.1007/BF00412592.

DOI:10.1007/BF00412592
PMID:3435175
Abstract

The effects of all-trans retinoic acid on human epidermal cell cultures were studied using ultrastructural techniques. Differentiation and stratification were reduced in retinoic acid treated epidermal cells. Treated cells developed a rounded appearance and seemed to contain more granules and vacuoles than usual. Desmosomes were not found in treated cells.

摘要

相似文献

1
Effects of all-trans retinoic acid on the morphology of human epidermal cells in vitro.
Arch Dermatol Res. 1987;279(7):459-64. doi: 10.1007/BF00412592.
2
Influence of retinoic acid on the ultrastructure and hyaluronic acid synthesis of adult human epidermis in whole skin organ culture.维甲酸对全皮肤器官培养中成人表皮超微结构和透明质酸合成的影响。
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The effect of all-trans-retinoic acid on the synthesis of epidermal cell-surface-associated carbohydrates.全反式维甲酸对表皮细胞表面相关碳水化合物合成的影响。
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Effects of retinoic acid on adult human epidermis in whole skin organ culture.
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Epidermal effects of retinoids: in vitro studies.维甲酸的表皮效应：体外研究
J Am Acad Dermatol. 1986 Oct;15(4 Pt 2):789-97. doi: 10.1016/s0190-9622(86)70235-1.
6
Hyaluronate accumulation in human epidermis treated with retinoic acid in skin organ culture.在皮肤器官培养中用视黄酸处理的人表皮中的透明质酸盐积累。
J Invest Dermatol. 1989 Mar;92(3):326-32. doi: 10.1111/1523-1747.ep12277125.
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Effect of retinoic acid and low calcium conditions on surface glycoconjugates defined by differential lectin labelling in mouse epidermal cell culture.维甲酸和低钙条件对小鼠表皮细胞培养中通过差异凝集素标记定义的表面糖缀合物的影响。
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Arch Dermatol Res. 1991;283(2):100-7. doi: 10.1007/BF00371617.
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All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.全反式维甲酸可刺激在缺乏生长因子的培养基中培养的成人角质形成细胞生长，抑制血小板反应蛋白和纤连蛋白的产生，并降低黏附性。
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Arch Dermatol Res. 1981;270(4):469-81. doi: 10.1007/BF00403792.

本文引用的文献

1
Effects of retinoic acid on the differentiation of hamster cheek pouch epithelium grown in vitro.视黄酸对体外培养的仓鼠颊囊上皮细胞分化的影响。
Scan Electron Microsc. 1981(Pt 3):383-9.
2
Retinoic acid causes premature desquamation of cells from confluent cultures of stratified squamous epithelia.视黄酸会导致分层鳞状上皮汇合培养物中的细胞过早脱屑。
J Invest Dermatol. 1982 Oct;79(4):253-60. doi: 10.1111/1523-1747.ep12500073.
3
Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia.
维生素A对源自不同人类上皮组织的培养角质形成细胞包膜交联的调节作用。
Mol Cell Biol. 1982 Sep;2(9):1115-7. doi: 10.1128/mcb.2.9.1115-1117.1982.
4
Effect of retinoic acid and low calcium conditions on surface glycoconjugates defined by differential lectin labelling in mouse epidermal cell culture.维甲酸和低钙条件对小鼠表皮细胞培养中通过差异凝集素标记定义的表面糖缀合物的影响。
Br J Dermatol. 1984 Jan;110(1):17-27. doi: 10.1111/j.1365-2133.1984.tb07307.x.
5
Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture.在化学成分明确的克隆培养和无血清连续培养中，正常人表皮角质形成细胞的钙调节分化
J Invest Dermatol. 1983 Jul;81(1 Suppl):33s-40s. doi: 10.1111/1523-1747.ep12540422.
6
Separation of the epidermal sheet by dispase.通过 dispase 分离表皮片。
Br J Dermatol. 1983 May;108(5):555-60. doi: 10.1111/j.1365-2133.1983.tb01056.x.
7
Cloning of cDNAs specifying vitamin A-responsive human keratins.
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4321-5. doi: 10.1073/pnas.81.14.4321.
8
Differences in keratin synthesis between normal epithelial cells and squamous cell carcinomas are mediated by vitamin A.正常上皮细胞与鳞状细胞癌之间角蛋白合成的差异由维生素A介导。
Proc Natl Acad Sci U S A. 1984 Jul;81(14):4280-4. doi: 10.1073/pnas.81.14.4280.
9
Bioassay of retinoids using cultured human conjunctival keratinocytes.
J Cell Physiol. 1984 May;119(2):172-4. doi: 10.1002/jcp.1041190205.
10
Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture. An ultrastructural study.培养中表皮细胞的细胞间接触及分化的钙调节。一项超微结构研究。
Exp Cell Res. 1983 Jan;143(1):127-42. doi: 10.1016/0014-4827(83)90115-5.