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[蛋白质营养不良对大鼠中性粒细胞吞噬功能的影响]

[Influence of protein malnutrition on the phagocytic function of neutrophils in rats].

作者信息

Garcia P B, Barbieri D

机构信息

Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Brasil.

出版信息

Arch Latinoam Nutr. 1986 Dec;36(4):662-77.

PMID:3435216
Abstract

A study was carried out to determine the effect of protein deficiency on the phagocytic function of blood neutrophils and of peritoneal exudate of rats. The deficient animals exhibited significantly lower leukocyte and neutrophil values, as well as NBT reduction and diminished peroxidase and bactericidal capacity. Englobement of S. aureus and latex particles was found to be normal in both groups. Alkaline phosphatase activity in the neutrophils appear to be increased in the deficient animals.

摘要

开展了一项研究以确定蛋白质缺乏对大鼠血液中性粒细胞和腹腔渗出液吞噬功能的影响。缺乏蛋白质的动物白细胞和中性粒细胞值显著降低,同时硝基四氮唑蓝还原、过氧化物酶和杀菌能力也减弱。两组中金黄色葡萄球菌和乳胶颗粒的吞噬情况均正常。缺乏蛋白质的动物中性粒细胞中的碱性磷酸酶活性似乎有所增加。

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