Abdollahi Mohammad-Bagher, Dehghan Somayeh Farhang, Balochkhaneh Faezeh Abasi, Moghadam Manouchehr Ahmadi, Mohammadi Hamzeh
Shoushtar Faculty of Medical Sciences, Shoushtar, Khuzestan, Iran.
Environmental and Occupational Hazards Control Research Center, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Environ Anal Health Toxicol. 2021 Sep;36(3):e2021013-0. doi: 10.5620/eaht.2021013. Epub 2021 Jul 13.
The present study was aimed to compare the effects of exposure to noise, vibration, lighting, and microwave on male mice' sperm parameters. The mice were randomly assigned to five groups of eight, which comprised of the unexposed group and exposure groups including the lighting (1000 lux), noise (100 dB(A)), vibration (acceleration of 1.2 m/s2) and microwave (power density of 5 watts). The exposure groups were subjected to the four agents for 8 hours a day, 5 days a week during a 2-week period. Semen analysis were done according to World Health Organization guidelines. The highest significant mean difference in sperm count (-1.35×106/mL) had being observed between the microwave group and the control one (P=0.001). The highest difference in immotile percent (25.88 %) had being observed between the noise group and the control one (P=0.001). The highest difference in normal morphology (-27.06 %) observed between the lighting exposure group and the control group (P=0.001). The four agents can cause changes in different sperm parameters, however for definite conclusion; more laboratory and field studies are required. In total, exposure to microwave has had the greatest effect on sperm count and exposure to light has had the greatest effect on normal morphology and non-progressive motility. Moreover, exposure to noise has had the greatest effect on progressive motility and immotile percent, respectively.
本研究旨在比较噪声、振动、光照和微波暴露对雄性小鼠精子参数的影响。将小鼠随机分为五组，每组八只，包括未暴露组和暴露组，暴露组包括光照（1000勒克斯）、噪声（100分贝（A））、振动（加速度为1.2米/秒²）和微波（功率密度为5瓦）。暴露组每天接受这四种因素暴露8小时，每周5天，持续2周。根据世界卫生组织指南进行精液分析。在微波组和对照组之间观察到精子计数的最高显著平均差异（-1.35×10⁶/毫升）（P = 0.001）。在噪声组和对照组之间观察到无活力百分比的最高差异（25.88%）（P = 0.001）。在光照暴露组和对照组之间观察到正常形态的最高差异（-27.06%）（P = 0.001）。这四种因素可导致不同精子参数发生变化，然而，要得出确切结论，还需要更多的实验室和现场研究。总体而言，微波暴露对精子计数的影响最大，光照暴露对正常形态和非进行性活力的影响最大。此外，噪声暴露分别对进行性活力和无活力百分比的影响最大。
