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工作场所的生殖毒性化学品及保护工人健康的努力:文献综述

Reproductive Toxic Chemicals at Work and Efforts to Protect Workers' Health: A Literature Review.

作者信息

Rim Kyung-Taek

机构信息

Chemicals Research Bureau, Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, Daejeon, 34122, Republic of Korea.

出版信息

Saf Health Work. 2017 Jun;8(2):143-150. doi: 10.1016/j.shaw.2017.04.003. Epub 2017 Apr 12.

DOI:10.1016/j.shaw.2017.04.003
PMID:28593069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5447413/
Abstract

A huge number of chemicals are produced and used in the world, and some of them can have negative effects on the reproductive health of workers. To date, most chemicals and work environments have not been studied for their potential to have damaging effects on the workers' reproductive system. Because of the lack of information, many workers may not be aware that such problems can be related to occupational exposures. Newly industrialized countries such as Republic of Korea have rapidly amassed chemicals and other toxicants that pose health hazards, especially to the reproductive systems of workers. This literature review provides an overview of peer-reviewed literature regarding the teratogenic impact and need for safe handling of chemicals. Literature searches were performed using PubMed, Google Scholar, and ScienceDirect. Search strategies were narrowed based on author expertise and 100 articles were chosen for detailed analysis. A total of 47 articles met prespecified inclusion criteria. The majority of papers contained studies that were descriptive in nature with respect to the Medical Subject Headings (MeSH) terms and keywords: "reproductive and heath or hazard and/or workplace or workers or occupations." In the absence of complete information about the safe occupational handling of chemicals in Republic of Korea (other than a material safety data sheet), this review serves as a valuable reference for identifying and remedying potential gaps in relevant regulations. The review also proposes other public health actions including hazard surveillance and primary prevention activities such as reduction, substitution, ventilation, as well as protective equipment.

摘要

世界上生产和使用着大量的化学品,其中一些可能会对工人的生殖健康产生负面影响。迄今为止,大多数化学品和工作环境尚未针对其对工人生殖系统产生破坏作用的可能性进行研究。由于信息匮乏,许多工人可能并未意识到此类问题可能与职业暴露有关。像韩国这样的新兴工业化国家迅速积累了对健康有害的化学品和其他有毒物质,尤其是对工人的生殖系统。这篇文献综述概述了关于化学品致畸影响及安全处理需求的同行评议文献。使用PubMed、谷歌学术和ScienceDirect进行文献检索。根据作者的专业知识缩小检索策略范围,选择了100篇文章进行详细分析。共有47篇文章符合预先设定的纳入标准。大多数论文包含的研究在医学主题词(MeSH)术语和关键词“生殖与健康或危害和/或工作场所或工人或职业”方面本质上是描述性的。鉴于韩国缺乏关于化学品安全职业处理的完整信息(除了物质安全数据表之外),本综述可为识别和弥补相关法规中的潜在差距提供有价值的参考。该综述还提出了其他公共卫生行动,包括危害监测和初级预防活动,如减少、替代、通风以及防护设备。

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Occupational exposure to pesticides, reproductive hormone levels and sperm quality in young Brazilian men.巴西年轻男性的农药职业暴露、生殖激素水平与精子质量
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