Zhang Yajun, Zhang Jinhui, Zhao Li, Zhao Na, Zhang Ye, Zhang Jie, Wang Shuying
Department of Laboratory, Beijing Renhe Hospital, Beijing, China.
Department of Laboratory, Laboratory of Changli People's Hospital, Changli, China.
Ann Palliat Med. 2021 Jul;10(7):8003-8014. doi: 10.21037/apm-21-1607.
Infectious disease is ubiquitous and can represent a major threat to human health. Procalcitonin (PCT) is mainly used to identify the severity of bacterial infections, which can be secondary to many non-bacterial infectious diseases. The purpose of this study was to evaluate current research in the field of infectious diseases and to suggest directions for further investigation.
The Science Citation Index Expanded (SCI-E) database in the Web of Science Core Collection (WOSCC) was used as the search data source. The search parameters including the search scope were limited to "infectious disease" and the search term was "procalcitonin". The time range of the target literature was 1900 to the final search date of this research (May 7, 2021), and the language was limited to English. The full records of the search results and cited references were exported in plain text format, and Citespace software was used to analyze the documents.
A total of 996 related research documents were found, and the number increased significantly in 2020. The United States, Germany, and the United Kingdom were the main sources of research, and the main research institutions were Aarhus University Hospital and Harvard University. The main journals are publishing material were Clin Infect Dis, Lancet, and Crit Care Med. Analysis of key words showed that the most common current research topics were sepsis and biomarkers of disease monitoring.
Research on infectious disease and the role of PCT is increasing. The main research topics are sepsis and biomarkers for disease monitoring.
传染病无处不在，可能对人类健康构成重大威胁。降钙素原（PCT）主要用于识别细菌感染的严重程度，而细菌感染可能继发于许多非细菌性传染病。本研究的目的是评估传染病领域的当前研究，并提出进一步研究的方向。
以Web of Science核心合集（WOSCC）中的科学引文索引扩展版（SCI-E）数据库作为搜索数据源。搜索参数包括搜索范围，限于“传染病”，搜索词为“降钙素原”。目标文献的时间范围为1900年至本研究的最终搜索日期（2021年5月7日），语言限于英语。搜索结果的完整记录和被引参考文献以纯文本格式导出，并使用Citespace软件对文献进行分析。
共找到996篇相关研究文献，2020年数量显著增加。美国、德国和英国是主要研究来源，主要研究机构是奥胡斯大学医院和哈佛大学。发表相关材料的主要期刊有《临床感染病杂志》《柳叶刀》和《危重病医学》。关键词分析表明，当前最常见的研究主题是脓毒症和疾病监测生物标志物。
关于传染病和PCT作用的研究正在增加。主要研究主题是脓毒症和疾病监测生物标志物。
