Hillman K
Department of Anaesthetics, Liverpool Hospital, Sydney, NSW, Australia.
Aust Paediatr J. 1987 Dec;23(6):343-6. doi: 10.1111/j.1440-1754.1987.tb00287.x.
The incidence of periventricular intraventricular haemorrhage (PVH-IVH) in premature infants with respiratory distress syndrome (RDS) remains at about 40%. Although there are certain inherent anatomical and physiological features of a neonate which predisposes them to PVH-IVH, there is conflicting evidence about the precipitating cause. The most significant antecedents of PVH-IVH are mechanical ventilation and barotrauma. This report examines the hypothesis that the final common pathway in PVH-IVH is fluctuation in intrathoracic pressure, and then attempts to explain previous anomalies and conflicting results which have implicated other causes. Suggestions are offered as to how changes in current management could contribute to a decreased incidence of this serious and widespread complication in premature infants with RDS.
患有呼吸窘迫综合征（RDS）的早产儿脑室周围脑室内出血（PVH-IVH）的发生率仍约为40%。尽管新生儿存在某些固有的解剖和生理特征，使他们易患PVH-IVH，但关于其诱发原因的证据存在矛盾。PVH-IVH最重要的前驱因素是机械通气和气压伤。本报告检验了这样一种假设，即PVH-IVH的最终共同途径是胸内压波动，然后试图解释先前涉及其他原因的异常情况和相互矛盾的结果。针对当前管理方式的改变如何有助于降低患有RDS的早产儿中这种严重且普遍存在的并发症的发生率提出了建议。
