Buhrich N, Cooper D A
Department of Psychiatry, St. Vincent's Hospital, Sydney, NSW.
Aust N Z J Psychiatry. 1987 Sep;21(3):346-53. doi: 10.1080/00048678709160931.
Psychiatric consultation was requested for 22 of 150 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) admitted to St Vincent's Hospital, Sydney. The mean age of the patients was 35 years and all were homosexual or bisexual men. Ten patients had an organic brain syndrome: six as a result of cerebral opportunistic infection, two due to metabolic or iatrogenic causes and two apparently due to the direct neurotropic effects of the human immunodeficiency virus (HIV). Hallucinations and delusions were documented in five patients, of whom two had symptoms that fulfilled the criteria for a diagnosis of functional psychosis. Four patients were diagnosed as having adjustment disorder-depressive mood and one patient may have had a major depressive illness. Marked denial of illness was seen in two patients and four had markedly slow mentation with only mild or no evidence of cognitive impairment. It is concluded that patients with AIDS may have a wide variety of neuropsychiatric manifestations.
悉尼圣文森特医院收治的150例获得性免疫缺陷综合征(AIDS)或AIDS相关综合征(ARC)患者中,有22例患者接受了精神科会诊。患者的平均年龄为35岁,均为同性恋或双性恋男性。10例患者患有器质性脑综合征:6例是由于脑部机会性感染,2例是由于代谢或医源性原因,2例显然是由于人类免疫缺陷病毒(HIV)的直接嗜神经作用。5例患者有幻觉和妄想,其中2例患者的症状符合功能性精神病的诊断标准。4例患者被诊断为适应性障碍-抑郁情绪,1例患者可能患有重度抑郁症。2例患者表现出明显的疾病否认,4例患者思维明显迟缓,仅有轻度认知障碍或无认知障碍迹象。结论是,AIDS患者可能有各种各样的神经精神表现。