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The use of antiviral Phthalocyanine mouthwash as a preventive measure against COVID-19.

作者信息

Vilhena Fabiano Vieira, Brito Reia Verônica Caroline, da Fonseca Orcina Bernardo, Santos Caíque Andrade, Zangrando Mariana, Cardoso de Oliveira Rodrigo, da Silva Santos Paulo Sérgio

机构信息

TRIALS - Oral Health & Technologies, Bauru, São Paulo, Brazil.

Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.

出版信息

GMS Hyg Infect Control. 2021 Jul 9;16:Doc24. doi: 10.3205/dgkh000395. eCollection 2021.

DOI:10.3205/dgkh000395
PMID:34354903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8299057/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d75/8299057/af84d14df084/HIC-16-24-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d75/8299057/7b5ef341a029/HIC-16-24-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d75/8299057/af84d14df084/HIC-16-24-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d75/8299057/7b5ef341a029/HIC-16-24-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d75/8299057/af84d14df084/HIC-16-24-g-001.jpg

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1
The use of antiviral Phthalocyanine mouthwash as a preventive measure against COVID-19.使用抗病毒酞菁漱口水作为预防 COVID-19 的措施。
GMS Hyg Infect Control. 2021 Jul 9;16:Doc24. doi: 10.3205/dgkh000395. eCollection 2021.
2
A Phthalocyanine Derivate Mouthwash to Gargling/Rinsing as an Option to Reduce Clinical Symptoms of COVID-19: Case Series.一种用于漱口/冲洗的酞菁衍生物漱口水作为减轻 COVID-19 临床症状的选择:病例系列
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Use of phthalocyanine-derived mouthwash as a protective factor for COVID-19: a community trial.使用酞菁衍生漱口水作为COVID-19的保护因素:一项社区试验。
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Effect of phthalocyanine oral and nasal antiseptic solutions on the infectivity of SARS-CoV-2 in patients with COVID-19: a randomized controlled trial.新型冠状病毒肺炎患者经口及鼻腔用酞菁口腔抗菌溶液对 SARS-CoV-2 感染力的影响:一项随机对照试验。
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Can the use of iron phthalocyanine-derivative mouthrinses in COVID-19 patients provide systemic benefits? Research into this potential should be considered.在新冠肺炎患者中使用铁酞菁衍生物漱口水能否带来全身益处?对此可能性的研究应予以考虑。
GMS Hyg Infect Control. 2024 Oct 2;19:Doc45. doi: 10.3205/dgkh000500. eCollection 2024.
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Use of phthalocyanine-derived mouthwash as a protective factor for COVID-19: a community trial.使用酞菁衍生漱口水作为COVID-19的保护因素:一项社区试验。
GMS Hyg Infect Control. 2024 Feb 21;19:Doc05. doi: 10.3205/dgkh000460. eCollection 2024.
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Efficacy of different mouthwashes against COVID-19: A systematic review and network meta-analysis.

本文引用的文献

1
Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial.一种含有抗病毒酞菁衍生物的漱口水对 COVID-19 住院时间的有益影响:随机试验。
Sci Rep. 2021 Oct 7;11(1):19937. doi: 10.1038/s41598-021-99013-5.
2
Virucidal Activity of the Antiseptic Mouthwash and Dental Gel Containing Anionic Phthalocyanine Derivative: In vitro Study.含阴离子酞菁衍生物的抗菌漱口水和牙科凝胶的杀病毒活性:体外研究
Clin Cosmet Investig Dent. 2021 Jun 28;13:269-274. doi: 10.2147/CCIDE.S315419. eCollection 2021.
3
Oral antiseptics against coronavirus: in-vitro and clinical evidence.
不同漱口水对新型冠状病毒肺炎的疗效:一项系统评价和网状Meta分析
Jpn Dent Sci Rev. 2023 Dec;59:334-356. doi: 10.1016/j.jdsr.2023.09.003. Epub 2023 Oct 11.
4
Population-based virucidal phthalocyanine gargling/rinsing protocol to reduce the risk of coronavirus disease-2019: a community trial.基于人群的杀病毒酞菁漱口/冲洗方案以降低2019冠状病毒病风险:一项社区试验。
GMS Hyg Infect Control. 2022 Dec 6;17:Doc23. doi: 10.3205/dgkh000426. eCollection 2022.
5
USE OF MOUTHWASH AND DENTIFRICE CONTAINING AN ANTIMICROBIAL PHTHALOCYANINE DERIVATIVE FOR THE REDUCTION OF CLINICAL SYMPTOMS OF COVID-19: A RANDOMIZED TRIPLE-BLIND CLINICAL TRIAL.使用含有抗菌酞菁衍生物的漱口水和牙膏来减轻 COVID-19 的临床症状:一项随机、三盲临床试验。
J Evid Based Dent Pract. 2022 Dec;22(4):101777. doi: 10.1016/j.jebdp.2022.101777. Epub 2022 Sep 14.
6
A recommendation of PHTALOX® for preventing infection and progression of COVID-19: a 1-year summarized update of scientific approaches.关于PHTALOX®预防新型冠状病毒肺炎感染及病情进展的建议:科学方法的1年总结更新
GMS Hyg Infect Control. 2022 Jan 31;17:Doc03. doi: 10.3205/dgkh000406. eCollection 2022.
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Interactions of Co, Cu, and non-metal phthalocyanines with external structures of SARS-CoV-2 using docking and molecular dynamics.利用对接和分子动力学研究 Co、Cu 和非金属酞菁与 SARS-CoV-2 外部结构的相互作用。
Sci Rep. 2022 Feb 28;12(1):3316. doi: 10.1038/s41598-022-07396-w.
8
Elimination of SARS-CoV-2 in nasopharynx and oropharynx after use of an adjuvant gargling and rinsing protocol with an antiseptic mouthwash.使用含抗菌漱口水的辅助漱口和冲洗方案后,鼻咽部和口咽部严重急性呼吸综合征冠状病毒2的清除情况
Einstein (Sao Paulo). 2022 Jan 5;19:eCE6999. doi: 10.31744/einstein_journal/2021CE6999. eCollection 2022.
抗冠状病毒的口腔抗菌剂:体外及临床证据
J Hosp Infect. 2021 Jul;113:30-43. doi: 10.1016/j.jhin.2021.04.004. Epub 2021 Apr 15.
4
A Phthalocyanine Derivate Mouthwash to Gargling/Rinsing as an Option to Reduce Clinical Symptoms of COVID-19: Case Series.一种用于漱口/冲洗的酞菁衍生物漱口水作为减轻 COVID-19 临床症状的选择:病例系列
Clin Cosmet Investig Dent. 2021 Feb 18;13:47-50. doi: 10.2147/CCIDE.S295423. eCollection 2021.
5
Virucidal gargling and virucidal nasal spray.具有杀病毒作用的漱口水和杀病毒鼻腔喷雾剂。
GMS Hyg Infect Control. 2021 Jan 18;16:Doc02. doi: 10.3205/dgkh000373. eCollection 2021.
6
Antiviral Activity of Reagents in Mouth Rinses against SARS-CoV-2.漱口水制剂抗 SARS-CoV-2 的抗病毒活性。
J Dent Res. 2021 Feb;100(2):124-132. doi: 10.1177/0022034520967933. Epub 2020 Oct 22.
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Virucidal Efficacy of Different Oral Rinses Against Severe Acute Respiratory Syndrome Coronavirus 2.不同漱口液对严重急性呼吸综合征冠状病毒 2 的病毒杀灭效果。
J Infect Dis. 2020 Sep 14;222(8):1289-1292. doi: 10.1093/infdis/jiaa471.