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一家大型创伤中心严重开放性胫骨干骨折的治疗策略与结果:一项大型回顾性病例系列研究

Strategies and outcomes in severe open tibial shaft fractures at a major trauma center: A large retrospective case-series.

作者信息

Patel Kavi H, Logan Karl, Krkovic Matija

机构信息

Department of Trauma & Orthopaedics, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, United Kingdom.

出版信息

World J Orthop. 2021 Jul 18;12(7):495-504. doi: 10.5312/wjo.v12.i7.495.

DOI:10.5312/wjo.v12.i7.495
PMID:34354937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8316841/
Abstract

BACKGROUND

Severe open tibia fractures are challenging to treat with a lack of published clear management strategies. Our aim was to provide an overview of the largest single-center experience in the literature, with minimum 1-year follow-up, of adult type 3 open tibial shaft fractures at Cambridge University Hospitals (a United Kingdom major trauma center). We sought to define patient characteristics and our main outcome measures were infection, union and re-fracture.

AIM

To retrospectively define patient and injury characteristics, present our surgical methods and analyze our outcomes-namely infection, union and re-fracture rates.

METHODS

Consecutive series of 74 patients with 75 open tibial fractures treated between 2014 and 2020 (26 classified as Gustilo-Anderson 3A, 47 were 3B and two were 3C). Nine patients underwent intramedullary nailing (IMN), 61 underwent Taylor spatial frame (TSF) fixation and 5 were treated with Masquelet technique (IMN and subsequent bone grafting).

RESULTS

Mean follow-up was 16 mo (IMN) and 25 mo (TSF). We had an infection rate of 6.7% (5), non-union rate of 4% (3) and re-fracture rate of 2.7% (2). Average time to union was 22 wk for IMN and 38.6 wk for TSF. Thirty-three cases had a bone defect with a mean of 5.4 cm (2-11). Patient age, sex, diabetes, smoking status or injury severity did not have a significant effect on union time with either fixation method. Our limb salvage rate was 98.7%.

CONCLUSION

Grade 1 to 3A injuries can effectively be treated with reamed or unreamed IMN. Grade 3B/C injuries are best treated by circular external fixators as they provide good, reproducible outcomes and allow large bone defects to be addressed distraction osteogenesis.

摘要

背景

严重开放性胫骨骨折的治疗颇具挑战,目前尚无已发表的明确治疗策略。我们的目的是对剑桥大学医院(英国一家主要创伤中心)成人3型开放性胫骨干骨折的最大单中心经验进行概述,随访时间至少为1年。我们试图明确患者特征,主要结局指标为感染、骨愈合及再骨折情况。

目的

回顾性明确患者及损伤特征,介绍我们的手术方法并分析结局,即感染、骨愈合及再骨折率。

方法

连续纳入2014年至2020年间74例患者的75例开放性胫骨骨折(26例为Gustilo-Anderson 3A,47例为3B,2例为3C)。9例患者接受髓内钉固定(IMN),61例接受泰勒空间框架(TSF)固定,5例采用Masquelet技术(IMN及随后的骨移植)治疗。

结果

平均随访时间为IMN组16个月,TSF组25个月。感染率为6.7%(5例),骨不连率为4%(3例),再骨折率为2.7%(2例)。IMN组平均骨愈合时间为22周,TSF组为38.6周。33例存在骨缺损,平均缺损5.4 cm(2 - 11 cm)。患者年龄、性别、糖尿病、吸烟状况或损伤严重程度对两种固定方法的骨愈合时间均无显著影响。我们的保肢率为98.7%。

结论

1至3A级损伤可通过扩髓或非扩髓IMN有效治疗。3B/C级损伤最好采用环形外固定器治疗,因为其能提供良好、可重复的结局,并允许通过牵张成骨处理大的骨缺损。

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