Clinical Neuroscience Research Unit, Department of Psychiatry, University of Vermont, Burlington, VT, USA.
Cousins Center for Psychoneuroimmunology and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.
Aging Ment Health. 2022 Sep;26(9):1765-1770. doi: 10.1080/13607863.2021.1958144. Epub 2021 Aug 6.
Although life stress has been associated with worse cognitive and psychiatric functioning, few studies on this topic have examined these associations in older adults and no studies to date have assessed lifetime stress exposure in this context.To address this important issue, we investigated associations between lifetime stress exposure, cognition, and psychiatric wellbeing in 44 women aged 60 and older who completed a comprehensive lifetime stress exposure inventory, two memory tasks, and a complete psychiatric assessment.As hypothesized, greater acute and chronic lifetime stress exposure were both related to poorer psychiatric functioning and more somatic health complaints. Greater lifetime stress exposure was also associated with poorer subjective cognition as indicated by memory and thought problems but not objective indices of memory function.Screening for high life stress exposure may therefore help identify older women at increased risk of experiencing negative psychiatric and cognitive outcomes.
尽管生活压力与认知和精神功能下降有关,但很少有研究关注这一话题在老年人中的关联,也没有研究评估过一生中在此背景下的压力暴露情况。为了解决这个重要的问题,我们调查了 44 名年龄在 60 岁及以上的女性一生中的压力暴露情况、认知和精神健康之间的关系,这些女性完成了一个全面的一生中压力暴露情况的清单、两个记忆任务和一个完整的精神科评估。正如假设的那样,更大的急性和慢性的生活压力暴露都与较差的精神功能和更多的躯体健康问题有关。更大的生活压力暴露也与较差的主观认知有关,如记忆和思维问题,但与记忆功能的客观指标无关。因此,对高生活压力暴露的筛查可能有助于识别出有更高风险经历负面精神和认知结果的老年女性。