Studenski S, Allen N B, Caldwell D S, Rice J R, Polisson R P
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.
Arthritis Rheum. 1987 Dec;30(12):1326-32. doi: 10.1002/art.1780301202.
We analyzed survival rate and important clinical outcomes in 411 patients with systemic lupus erythematosus who were seen at our center between 1969 and 1984. All eligible subjects met 4 of the revised American Rheumatism Association criteria for systemic lupus erythematosus and all were seen within 2 years of diagnosis. Mean followup was 75.6 months. Multivariate analysis suggested significant independent effects of race (P = 0.0139) and socioeconomic status (P = 0.0326) on survival. No evidence of diminished lupus-related mortality with age was documented. Previously reported findings of improved survival rate with age may have been confounded by differences in race distribution between the younger- and older-onset groups.
我们分析了1969年至1984年间在我们中心就诊的411例系统性红斑狼疮患者的生存率和重要临床结局。所有符合条件的受试者均符合美国风湿病学会修订的系统性红斑狼疮标准中的4条，且均在诊断后2年内就诊。平均随访时间为75.6个月。多变量分析表明，种族（P = 0.0139）和社会经济地位（P = 0.0326）对生存有显著的独立影响。未发现狼疮相关死亡率随年龄降低的证据。先前报道的生存率随年龄提高的结果可能因年轻发病组和老年发病组之间种族分布的差异而混淆。
