Williams W V, Cope R, Gaunt W D, Adelstein E H, Hoyt T S, Singh A, Pressly T A, English R, Schumacher H R, Walker S E
Veterans Administration Medical Center, Columbia, Missouri.
Arthritis Rheum. 1987 Dec;30(12):1362-71. doi: 10.1002/art.1780301207.
We describe 7 manual laborers with painful, palpably enlarged metacarpophalangeal joints. Characteristic radiographic changes were joint space loss, prominent osteophytes, and cystic metacarpal heads most prominent in the second and third metacarpophalangeal joints. In 3 of 4 patients, joint biopsy specimens showed subsynovial fibrosis and villous hyperplasia. All 7 patients had similar backgrounds of heavy work demanding sustained gripping motions of both hands, for periods that exceeded 30 years. We designated their condition metacarpophalangeal arthropathy associated with manual labor.
我们描述了7名患有疼痛且可触及掌指关节肿大的体力劳动者。特征性的影像学改变为关节间隙变窄、明显的骨赘形成以及第二和第三掌指关节处最为突出的囊性掌骨头。4例患者中有3例的关节活检标本显示滑膜下纤维化和绒毛状增生。所有7例患者都有相似的高强度工作背景,双手需要持续抓握动作,且持续时间超过30年。我们将他们的病症命名为与体力劳动相关的掌指关节病。