口服预防性维生素K后[校正的]血清凝血酶原浓度
Acarboxyprothrombin concentration [corrected] after oral prophylactic vitamin K.
作者信息
von Kries R, Kreppel S, Becker A, Tangermann R, Göbel U
机构信息
Department of Paediatrics, University of Düsseldorf, Federal Republic of Germany.
出版信息
Arch Dis Child. 1987 Sep;62(9):938-40. doi: 10.1136/adc.62.9.938.
Abstract
The effect of prophylaxis with oral vitamin K (1 mg vitamin K1 given with the first feed) on the rate of detection of acarboxyprothrombin (PIVKA II) and factor II clotting concentration [corrected] were analysed. Introducing such prophylaxis reduced the rates of detection of PIVKA II concentration [corrected] on day 5 from 48% to zero. None of the babies given prophylaxis had factor II clotting concentration [corrected] below 40%, compared with 34 of 95 babies not given prophylaxis. This study has important implications in the prophylaxis of both classical and late onset haemorrhagic disease of the newborn.
摘要
分析了口服维生素K（首次喂养时给予1毫克维生素K1）预防对异常凝血酶原（PIVKA II）检测率和凝血因子II浓度[校正后]的影响。采用这种预防措施可使第5天PIVKA II浓度[校正后]的检测率从48%降至零。接受预防的婴儿中，没有一个的凝血因子II浓度[校正后]低于40%，而未接受预防的95名婴儿中有34名低于40%。这项研究对新生儿经典型和晚发型出血性疾病的预防具有重要意义。
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本文引用的文献
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J Pediatr. 1962 Nov;61:686-92. doi: 10.1016/s0022-3476(62)80339-4.
2
A haematocrit corrected micro determination of the P&P-test and blood clotting factors in capillary blood.血细胞比容校正的毛细血管血中血小板与血浆比值试验及凝血因子的微量测定。
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