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多次输血的β地中海贫血患儿的淋巴结病综合征与HIV感染

Lymphadenopathy syndrome and HIV infection in multitransfused beta-thalassemia child.

作者信息

Schettini F, De Mattia D, Fumarola D, Pollice L

机构信息

Institute of Clinical and Preventive Pediatrics, University of Bari, School of Medicine, Italy.

出版信息

Boll Ist Sieroter Milan. 1987;66(3):235-8.

PMID:3435653
Abstract

Lymphoadenopathic Syndrome (LAS), diagnosed also with histologycal studies, is described in a polytransfused 11-year old boy affected by beta-thalassemia major. After three days of the admission he suffered a serious acute diarrhea by Aeromonas hydrophila, an opportunistic enteric bacteria demonstrated, up to date, in immunocompromised patients and never in AIDS patients. It is important to remark that beta-thalassemic patients are at high risk from HIV infections, either for the chronic need of transfusions and for the impairment of the immunological functions.

摘要

淋巴结病综合征(LAS),经组织学研究确诊,在一名患有重型β地中海贫血的11岁多次输血男孩中被描述。入院三天后,他因嗜水气单胞菌感染患上严重急性腹泻,嗜水气单胞菌是一种机会性肠道细菌,迄今为止已在免疫功能低下患者中发现,但从未在艾滋病患者中发现。必须指出的是,β地中海贫血患者因长期需要输血和免疫功能受损,感染艾滋病毒的风险很高。

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