Tsakalos Anastasios, Xirogianni Athanasia, Ekonomou Georgia, Papandreou Anastasia, Prokopiou Efstratios, Vagiakou Eleni, Tzanakaki Georgina
Microbiology Department, "Georgios Gennimatas" General Hospital of Athens, 11527 Athens, Greece.
National Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 11521 Athens, Greece.
Diagnostics (Basel). 2021 Jul 14;11(7):1265. doi: 10.3390/diagnostics11071265.
is considered as an obligate human pathogen and can cause life-threatening diseases like meningitis and/or septicaemia. Occasionally, it can be recovered from infections outside the bloodstream or central nervous system, like respiratory, ocular, joint, urogenital or other unusual sites. Herein, we present two rare cases of female genital infections due to within a two-year period (2019-2020), identified as serogroup B (MenB) and Y (MenY), respectively. Genotypic analysis for PorA, FetA and MLST revealed the following characteristics: MenB: 7-12, 14, F5-36, 1572cc and MenY: 5-1,10-1, F4-5, 23cc, respectively. Such unusual presentations should alert the clinicians and microbiologists not to exclude . from routine diagnosis and the need of early detection. This is the first report in Greece, and, to our knowledge, in Europe since 2005 describing meningococcal female genital infections.
被认为是一种专性人类病原体，可引起危及生命的疾病，如脑膜炎和/或败血症。偶尔，它也可从血液或中枢神经系统以外的感染中分离出来，如呼吸道、眼部、关节、泌尿生殖系统或其他不寻常部位。在此，我们报告了两例罕见的女性生殖器感染病例，在两年时间（2019 - 2020年）内分别由血清群B（MenB）和血清群Y（MenY）引起。对PorA、FetA和多位点序列分型（MLST）的基因分析显示了以下特征：MenB分别为7 - 12、14、F5 - 36、1572cc，MenY分别为5 - 1、10 - 1、F4 - 5、23cc。这种不寻常的表现应提醒临床医生和微生物学家在常规诊断中不要排除 ，并需要早期检测。这是希腊的首例报告，据我们所知，也是自2005年以来欧洲首例描述脑膜炎球菌性女性生殖器感染的报告。
