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开发一种加速稳定性模型以估算紫玉米芯提取物粉末(Moradyn)的保质期。

Development of an Accelerated Stability Model to Estimate Purple Corn Cob Extract Powder (Moradyn) Shelf-Life.

作者信息

Ferron Lucia, Milanese Chiara, Colombo Raffaella, Papetti Adele

机构信息

Department of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

FlaNat Research Italia Srl, Via Giuseppe di Vittorio 1, 20017 Rho, Milan, Italy.

出版信息

Foods. 2021 Jul 13;10(7):1617. doi: 10.3390/foods10071617.

DOI:10.3390/foods10071617
PMID:34359487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8307474/
Abstract

Moradyn is an Italian purple corn variety whose cobs represent a rich source of polyphenols. At the industrial level, they are used to produce a dried extract (MCE) by the addition of 20% Arabic gum. In order to evaluate the extract solid-state stability, an innovative accelerated stress protocol was developed following the isoconversion approach. The degradation kinetics of cyanidin-3--glucoside (C3G), the most suitable marker to monitor the overall MCE degradation status, was monitored under five temperature-humidity (RH) combinations. These data were used to build a mathematical model, able to estimate the C3G stability at 25 °C and 30% RH, whose predictiveness was further assessed by comparing the predicted vs. experimental C3G isoconversion time. Finally, by applying this model, the expiry date of the extract was calculated to be within 26-33 days, confirming that the addition of 20% Arabic gum is insufficient to stabilize MCE and highlighting the need of a new formula in order to prolong MCE shelf-life.

摘要

莫拉迪恩是一种意大利紫玉米品种,其玉米穗轴是多酚的丰富来源。在工业层面,通过添加20%阿拉伯胶,它们被用于生产一种干燥提取物(MCE)。为了评估提取物的固态稳定性,遵循等转化率方法开发了一种创新的加速应力方案。在五种温度-湿度(RH)组合下监测了矢车菊素-3-葡萄糖苷(C3G)的降解动力学,C3G是监测MCE整体降解状态的最合适标志物。这些数据被用于建立一个数学模型,该模型能够估计25℃和30%RH条件下C3G的稳定性,通过比较预测的和实验的C3G等转化率时间进一步评估其预测能力。最后,通过应用该模型,计算出提取物的有效期在26至33天内,证实添加20%阿拉伯胶不足以稳定MCE,并突出了需要一种新配方来延长MCE保质期的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb2/8307474/6f51e304c69f/foods-10-01617-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb2/8307474/ba062fcab59f/foods-10-01617-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb2/8307474/6f51e304c69f/foods-10-01617-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb2/8307474/ba062fcab59f/foods-10-01617-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb2/8307474/6f51e304c69f/foods-10-01617-g005.jpg

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