Department of Gynecological Surgery and Oncology of Adults and Adolescents, Pomeranian Medical University, 70-111 Szczecin, Poland.
Department of Gynecology and Reproductive Health, Pomeranian Medical University, 71-210 Szczecin, Poland.
Int J Environ Res Public Health. 2021 Jul 24;18(15):7851. doi: 10.3390/ijerph18157851.
Rhabdomyosarcoma of the cervix is a soft tissue sarcoma that usually occurs in young women. It is very rare in adulthood. We discuss symptoms, the process of diagnosis of rhabdomyosarcoma embryonale of the cervix in a 61-year-old women and differences in treatment dependent on patient's age. A 61-year-old woman with symptoms such as palpable mass in the external cervical opening and post-menopausal hemorrhaging was admitted to the oncology ward where excision of the polyp was performed. Embryonal rhabdomyosarcoma (ERMS) was diagnosed by histopathological examination of obtained tissues. The diagnosis was complemented by chest computed tomography and pelvis magnetic resonance imaging to exclude metastases. A Wertheim-Meigs operation and excision of the ovaries, the fallopian tubes and the surrounding tissue was performed in the course of treatment. In the patient's follow-up of 25 months to date, there have been no signs of recurrence or symptoms connected to ERMS. Based on the therapeutic outcome, the decision to limit the treatment to a surgical resection was adequate for a post-menopausal patient. Because of the rarity of ERMS in the post-menopausal age, we think that the patient should be carefully followed up to further examine this issue and develop diagnostic and treatment guidelines.
宫颈横纹肌肉瘤是一种软组织肉瘤，通常发生在年轻女性中。在成年期非常罕见。我们讨论了一位 61 岁女性宫颈胚胎性横纹肌肉瘤的症状、诊断过程以及因患者年龄不同而导致的治疗差异。一位 61 岁的女性出现了宫颈外口可触及肿块和绝经后出血等症状，被收入肿瘤科病房，在那里进行了息肉切除术。通过对获得的组织进行组织病理学检查，诊断为胚胎性横纹肌肉瘤（ERMS）。胸部计算机断层扫描和骨盆磁共振成像的诊断结果补充了该诊断，以排除转移。在治疗过程中，进行了经腹广泛子宫切除术+双侧附件切除术+盆腔淋巴结清扫术。在对患者的 25 个月随访中，目前尚无复发迹象或与 ERMS 相关的症状。基于治疗结果，对绝经后患者进行手术切除的治疗决策是充分的。由于绝经后 ERMS 罕见，我们认为应仔细随访该患者，进一步检查这一问题，并制定诊断和治疗指南。
