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父母社会经济地位和身体活动与青春期前儿童动脉僵硬度发育的关系。

Association of Parental Socioeconomic Status and Physical Activity with Development of Arterial Stiffness in Prepubertal Children.

机构信息

Department of Sport, Exercise and Health, Medical Faculty, University of Basel, 4052 Basel, Switzerland.

出版信息

Int J Environ Res Public Health. 2021 Aug 3;18(15):8227. doi: 10.3390/ijerph18158227.

DOI:10.3390/ijerph18158227
PMID:34360513
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8346041/
Abstract

The present study examined the prospective association of parental household income, education level, migration background, and physical activity (PA) behavior with the development of pulse wave velocity (PWV) in prepubertal children. A total of 223 children (initial age 6-8 years) were included in this prospective school-based cohort study from 2014 to 2018. Parental socioeconomic status, migration background, and PA behavior were assessed by the use of questionnaires at both times points. PWV was measured by an oscillometric device at follow-up (2018). No significant association of household income, education level, and parental migration background with PWV in children after four years was found. However, a high level of maternal PA was related to a lower childhood PWV at follow-up (mean (95% CI) 4.6 (4.54-4.66) m/s) compared to children of mothers with a low PA behavior (mean (95% CI) 4.7 (4.64-4.77) m/s) ( = 0.049). Children of mothers with a high PA level revealed a beneficial arterial stiffness after four years. Little evidence for an association of socioeconomic status and migration background with childhood arterial stiffness was found. Increased parental PA seems to support the development of childhood vascular health and should be considered in the generation of future primary prevention strategies of childhood cardiovascular health.

摘要

本研究旨在探讨父母家庭收入、教育水平、移民背景和体力活动(PA)行为与青春期前儿童脉搏波速度(PWV)发展的前瞻性关联。这项前瞻性的基于学校的队列研究于 2014 年至 2018 年期间共纳入了 223 名儿童(初始年龄为 6-8 岁)。在两个时间点,通过使用问卷评估了父母的社会经济地位、移民背景和 PA 行为。在随访时(2018 年),通过示波法设备测量 PWV。经过四年,家庭收入、教育水平和父母移民背景与儿童 PWV 之间没有显著关联。然而,与母亲 PA 行为较低的儿童相比(均值(95%CI)4.7(4.64-4.77)m/s),母亲 PA 水平较高的儿童在随访时的儿童 PWV 较低(均值(95%CI)4.6(4.54-4.66)m/s)(=0.049)。PA 水平较高的母亲的孩子在四年后表现出有益的动脉僵硬。社会经济地位和移民背景与儿童动脉僵硬之间的关联几乎没有证据。增加父母的 PA 似乎有助于儿童血管健康的发展,应在制定未来儿童心血管健康初级预防策略时加以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793c/8346041/4adadb0fc55d/ijerph-18-08227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793c/8346041/4adadb0fc55d/ijerph-18-08227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/793c/8346041/4adadb0fc55d/ijerph-18-08227-g001.jpg

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2
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Pediatr Res. 2022 Feb;91(3):502-512. doi: 10.1038/s41390-020-01278-5. Epub 2021 Apr 6.
3
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Front Physiol. 2020 Dec 17;11:613003. doi: 10.3389/fphys.2020.613003. eCollection 2020.
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Psychoneuroendocrinology. 2021 Jan;123:104917. doi: 10.1016/j.psyneuen.2020.104917. Epub 2020 Oct 17.
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