J Phys Act Health. 2020 Aug 24;17(10):933-939. doi: 10.1123/jpah.2019-0594.
Physical activity (PA) has a substantial impact on arterial stiffness in adults; however, evidence regarding children is scarce. The aim of this study was to examine the association between objectively measured PA with different intensities and surrogate measures of arterial stiffness in healthy children.
Altogether, 80 children (41 girls and 39 boys, ranging from 8-11 y) participated in this prospective, cross-sectional study. Sedentary time and PA of light, moderate, and vigorous intensity levels were measured over a period of 7 days by accelerometry. Arterial stiffness parameters, including pulse wave velocity and central systolic blood pressure (cSBP), were noninvasively assessed by the oscillometric Mobil-O-Graph. Associations were tested using multiple linear regressions with adjustments for potential confounders (α ≤ .05).
PA of moderate intensity was negatively associated with cSBP (β = -0.266, P = .017). PA of vigorous intensity was inversely related to pulse wave velocity (β = -0.225, P = .045) and cSBP (β = -0.286, P = .010), respectively.
Higher time spent in PA of moderate and vigorous intensity is associated with reduced pulse wave velocity and lower cSBP values in children. It suggests that PA is a favorable determinant of arterial health.
身体活动(PA)对成年人的动脉僵硬有很大影响;然而,关于儿童的证据很少。本研究的目的是检查健康儿童中不同强度的客观测量 PA 与动脉僵硬替代指标之间的关系。
共有 80 名儿童(41 名女孩和 39 名男孩,年龄 8-11 岁)参加了这项前瞻性、横断面研究。通过加速度计在 7 天内测量久坐时间和轻、中、高强度水平的 PA。通过无创伤的示波法 Mobil-O-Graph 评估动脉僵硬参数,包括脉搏波速度和中心收缩压(cSBP)。使用多元线性回归模型,调整潜在混杂因素(α≤.05)后,对关联进行测试。
中强度 PA 与 cSBP 呈负相关(β=-0.266,P=0.017)。高强度 PA 与脉搏波速度(β=-0.225,P=0.045)和 cSBP(β=-0.286,P=0.010)呈负相关。
中高强度 PA 时间的增加与儿童脉搏波速度降低和 cSBP 值降低有关。这表明 PA 是动脉健康的有利决定因素。