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2005 - 2018年美国成年人类风湿关节炎的患病率趋势及差异

Prevalence Trend and Disparities in Rheumatoid Arthritis among US Adults, 2005-2018.

作者信息

Xu Yingke, Wu Qing

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.

Nevada Institute of Personalized Medicine, College of Sciences, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.

出版信息

J Clin Med. 2021 Jul 26;10(15):3289. doi: 10.3390/jcm10153289.

Abstract

Rheumatoid arthritis (RA) trends among US adults and disparities in RA patients in recent years have not been well described. We aimed to examine the trend of RA prevalence and disparities among US adults. Data from the National Health and Nutrition Examination Survey (NHANES) of the years 2005-2018 were analyzed to examine the self-reported RA prevalence trend. Age-adjusted RA prevalence stratified by race/ethnicity and socioeconomic status (SES), as well as associated linear trends, were calculated for both genders. The multivariable adjustment was used to evaluate the association between race, SES, and RA. During 2005-2018, there was no significant linear trend in the age-adjusted self-reported RA prevalence among men and women, but significant differences among people from different races, educational levels, and family poverty income ratio (PIR) groups were observed. The RA rate difference was significant for both genders and between Non-Hispanic Caucasians and Non-Hispanic African Americans (both -value ≤ 0.001). Both men and women with a higher educational level and a higher PIR had a lower age-adjusted RA rate. Age-adjusted RA prevalence fluctuated for both men and women during 2005-2018. Non-Hispanic African Americans and people with low SES had significantly higher age-adjusted RA prevalence and RA risk.

摘要

美国成年人中类风湿性关节炎(RA)的发病趋势以及近年来RA患者的差异尚未得到充分描述。我们旨在研究美国成年人中RA患病率的趋势及其差异。分析了2005 - 2018年国家健康与营养检查调查(NHANES)的数据,以研究自我报告的RA患病率趋势。计算了按种族/族裔和社会经济地位(SES)分层的年龄调整后的RA患病率以及相关的线性趋势,男女均进行了计算。采用多变量调整来评估种族、SES与RA之间的关联。在2005 - 2018年期间,男女年龄调整后的自我报告RA患病率没有显著的线性趋势,但观察到不同种族、教育水平和家庭贫困收入比(PIR)组之间存在显著差异。RA发病率差异在男女以及非西班牙裔白人和非西班牙裔非裔美国人之间均具有显著性(均P值≤0.001)。教育水平较高和PIR较高的男性和女性年龄调整后的RA发病率较低。2005 - 2018年期间,男女年龄调整后的RA患病率均有波动。非西班牙裔非裔美国人和SES较低的人群年龄调整后的RA患病率和RA风险显著更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a595/8348893/19db58657d8a/jcm-10-03289-g001.jpg

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