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针对有创通气的危重症成年患者的气道护理干预措施——一项荷兰全国性调查

Airway Care Interventions for Invasively Ventilated Critically Ill Adults-A Dutch National Survey.

作者信息

Stilma Willemke, van der Hoeven Sophia M, Scholte Op Reimer Wilma J M, Schultz Marcus J, Rose Louise, Paulus Frederique

机构信息

Center of Expertise Urban Vitality, Faculty of Health, Amsterdam University of Applied Science, 1105 BD Amsterdam, The Netherlands.

Department of Intensive Care Medicine, Amsterdam University Medical Centers, Location AMC, 1105 AZ Amsterdam, The Netherlands.

出版信息

J Clin Med. 2021 Jul 30;10(15):3381. doi: 10.3390/jcm10153381.

Abstract

Airway care interventions may prevent accumulation of airway secretions and promote their evacuation, but evidence is scarce. Interventions include heated humidification, nebulization of mucolytics and/or bronchodilators, manual hyperinflation and use of mechanical insufflation-exsufflation (MI-E). Our aim is to identify current airway care practices for invasively ventilated patients in intensive care units (ICU) in the Netherlands. A self-administered web-based survey was sent to a single pre-appointed representative of all ICUs in the Netherlands. Response rate was 85% (72 ICUs). We found substantial heterogeneity in the intensity and combinations of airway care interventions used. Most (81%) ICUs reported using heated humidification as a routine prophylactic intervention. All (100%) responding ICUs used nebulized mucolytics and/or bronchodilators; however, only 43% ICUs reported nebulization as a routine prophylactic intervention. Most (81%) ICUs used manual hyperinflation, although only initiated with a clinical indication like difficult oxygenation. Few (22%) ICUs used MI-E for invasively ventilated patients. Use was always based on the indication of insufficient cough strength or as a continuation of home use. In the Netherlands, use of routine prophylactic airway care interventions is common despite evidence of no benefit. There is an urgent need for evidence of the benefit of these interventions to inform evidence-based guidelines.

摘要

气道护理干预措施可能会防止气道分泌物积聚并促进其排出,但相关证据较少。干预措施包括加热湿化、黏液溶解剂和/或支气管扩张剂雾化、手动过度通气以及使用机械通气辅助咳痰(MI-E)。我们的目的是确定荷兰重症监护病房(ICU)中接受有创通气患者当前的气道护理做法。我们向荷兰所有ICU预先指定的一名代表发送了一份基于网络的自填式调查问卷。回复率为85%(72个ICU)。我们发现所使用的气道护理干预措施的强度和组合存在很大差异。大多数(81%)ICU报告将加热湿化作为常规预防性干预措施。所有(100%)回复的ICU都使用雾化黏液溶解剂和/或支气管扩张剂;然而,只有43%的ICU报告将雾化作为常规预防性干预措施。大多数(81%)ICU使用手动过度通气,不过仅在出现如氧合困难等临床指征时才开始使用。很少有(22%)ICU对接受有创通气的患者使用MI-E。其使用总是基于咳嗽力量不足的指征或作为家庭使用的延续。在荷兰,尽管没有证据表明有益,但常规预防性气道护理干预措施的使用很普遍。迫切需要这些干预措施有益的证据来为循证指南提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6333/8347919/50e419200683/jcm-10-03381-g001.jpg

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